口腔肿瘤学中体内自体荧光光谱学与成像的现状

The status of in vivo autofluorescence spectroscopy and imaging for oral oncology.

作者信息

De Veld D C G, Witjes M J H, Sterenborg H J C M, Roodenburg J L N

机构信息

Department of Oral and Maxillofacial Surgery, Division of Oncology, University Hospital Groningen, P.O. Box 30 001, Groningen 9700, The Netherlands.

出版信息

Oral Oncol. 2005 Feb;41(2):117-31. doi: 10.1016/j.oraloncology.2004.07.007.

DOI:10.1016/j.oraloncology.2004.07.007

PMID:15695112

Abstract

Autofluorescence spectroscopy and imaging have been studied for the early detection and classification of (pre)malignancies of the oral mucosa. In the present review we will give an overview of the literature on autofluorescence imaging and spectroscopy for various clinical questions. From the studies performed so far we hope to conclude whether autofluorescence spectroscopy and imaging are helpful in the diagnosis of lesions of the oral mucosa, and if this is the case: for which clinical questions they are suitable. A strong emphasis is put on in vivo human studies of the oral mucosa.

摘要

自体荧光光谱学和成像技术已被用于口腔黏膜（癌前）病变的早期检测和分类研究。在本综述中，我们将概述有关自体荧光成像和光谱学在各种临床问题上的文献。从目前已开展的研究中，我们希望得出自体荧光光谱学和成像技术是否有助于口腔黏膜病变的诊断，如果是这样：它们适用于哪些临床问题。本文重点关注口腔黏膜的人体活体研究。