Soetikno Roy M, Kahng Lyn Sue, Ono Akiko, Fujii Takahiro
Veterans Affairs, Palo Alto Health Care System and Stanford University, Palo Alto, California, USA.
Curr Opin Gastroenterol. 2003 Jan;19(1):69-75. doi: 10.1097/00001574-200301000-00012.
An increasing body of literature is available showing the existence of flat and depressed colorectal neoplasms in Western countries. The appreciation that colorectal neoplasms may present as flat or depressed lesions has important implications, as the risk of adenocarcinoma in depressed lesions has been found to be markedly higher than in flat or protruding lesions of similar size. There is concern that flat or depressed colorectal neoplasms might be easily missed during a colonoscopy and subsequently diagnosed as cancer within a few years after a clearing examination. In this review, we appraise advances in the study of flat and depressed colorectal cancers based on the English literature published in 2000 and subsequently, with emphasis on their epidemiology, diagnosis, and therapy.
越来越多的文献表明，西方国家存在扁平状和凹陷状的结直肠肿瘤。认识到结直肠肿瘤可能表现为扁平或凹陷性病变具有重要意义，因为已发现凹陷性病变中腺癌的风险明显高于类似大小的扁平或突出性病变。人们担心，扁平或凹陷性结直肠肿瘤在结肠镜检查时可能很容易被漏诊，随后在清除检查后的几年内被诊断为癌症。在本综述中，我们根据2000年及之后发表的英文文献评估扁平状和凹陷状结直肠癌的研究进展，重点关注其流行病学、诊断和治疗。
