结肠镜检查前肠道准备的时机决定了清洁质量，并且是影响扁平病变检出的一个重要因素：一项随机研究。
The timing of bowel preparation before colonoscopy determines the quality of cleansing, and is a significant factor contributing to the detection of flat lesions: a randomized study.
作者信息
Parra-Blanco Adolfo, Nicolas-Perez David, Gimeno-Garcia Antonio, Grosso Begona, Jimenez Alejandro, Ortega Juan, Quintero Enrique
机构信息
Servicio de Aparato Digestivo, Unidad de Endoscopia (10(a) Planta), Hospital Universitario de Canarias, C/Ofra s/n, 38320 La Laguna, Santa Cruz de Tenerife, Spain.
出版信息
World J Gastroenterol. 2006 Oct 14;12(38):6161-6. doi: 10.3748/wjg.v12.i38.6161.
Abstract
AIM
To compare the cleansing quality of polyethylene glycol electrolyte solution and sodium phosphate with different schedules of administration, and to evaluate whether the timing of the administration of bowel preparation affects the detection of polyps.
METHODS
One hundred and seventy-seven consecutive outpatients scheduled for colonoscopy were randomized in one of four groups to receive polyethylene glycol electrolyte solution or oral sodium phosphate with two different timing schedules. Quality of cleansing, polyp detection, and tolerance were evaluated.
RESULTS
Patients receiving polyethylene glycol or sodium phosphate on the same day as the colonoscopy, obtained good to excellent global cleansing scores more frequently than patients who received polyethylene glycol or sodium phosphate on the day prior to the procedure (P < 0.001). Flat lesions, but not flat adenomas, were more frequent in patients prepared on the same day (P = 0.02).
CONCLUSION
The quality of colonic cleansing and the detection of flat lesions are significantly improved when the preparation is taken on the day of the colonoscopy.
摘要
目的
比较不同给药方案下聚乙二醇电解质溶液和磷酸钠的清洁质量，并评估肠道准备的给药时间是否会影响息肉的检测。
方法
177例连续安排进行结肠镜检查的门诊患者被随机分为四组，分别接受聚乙二醇电解质溶液或口服磷酸钠，并采用两种不同的给药时间安排。对清洁质量、息肉检测和耐受性进行评估。
结果
在结肠镜检查当天接受聚乙二醇或磷酸钠的患者，获得良好至优秀的整体清洁评分的频率高于在检查前一天接受聚乙二醇或磷酸钠的患者（P < 0.001）。在当天进行肠道准备的患者中，扁平病变（而非扁平腺瘤）更为常见（P = 0.02）。
结论
在结肠镜检查当天进行肠道准备时，结肠清洁质量和扁平病变的检测显著改善。
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