Neuhauser Beate, Czermak Benedikt V, Fish John, Perkmann Reinhold, Jaschke Werner, Chemelli Andreas, Fraedrich Gustav
Departments of Vascular Surgery, University Hospital Innsbruck, A-6020 Innsbruck, Austria.
J Endovasc Ther. 2005 Feb;12(1):74-81. doi: 10.1583/04-1369.1.
To describe our experience with endovascular stent-graft repairs in the thoracic aorta focusing on the secondary complication of type A dissection.
Between January 1996 and April 2004, 73 patients were treated for traumatic thoracic aortic rupture (n=15), type B dissection (n=22), or atherosclerotic descending thoracic aortic aneurysms (TAA, n=36). A retrospective review of the records found 5 (6.8%) patients (3 men; median age 64 years, range 43-87) who experienced a type A dissection at a median 20 days (range 2-124) after thoracic stent-graft repair for 3 type B dissections, 1 TAA, and a late type I endoleak that appeared 28 months after initial stent-graft repair of a traumatic dissection.
In 3 patients (2 dissections, 1 endoleak), a tear in the aortic wall at the proximal stent-graft was responsible for a retrograde type A dissection. Underlying disease was the cause of the type A dissection in the 2 other patients (1 dissection, 1 TAA) and was unrelated to the stent-grafts. Three patients underwent open surgery at 3, 26, and 124 days after stent-graft placement; 2 procedures were successful, but the third patient died 3 months later due to multiorgan failure. Two type A dissections were untreated: one patient died from cardiac tamponade 14 days after successful stent-graft exclusion of the type I endoleak; the other patient refused further treatment and survived. The procedure-related mortality following acute retrograde type A dissection was 40%.
Endovascular stent-graft repair of the thoracic aorta is associated with lower morbidity and mortality rates than surgical repair, although potentially lethal complications, acute or delayed, may occur.
描述我们在胸主动脉腔内支架移植物修复方面的经验,重点关注A型夹层的继发性并发症。
1996年1月至2004年4月期间,73例患者接受了创伤性胸主动脉破裂(n = 15)、B型夹层(n = 22)或动脉粥样硬化性降主动脉瘤(TAA,n = 36)的治疗。对记录进行回顾性分析发现,5例(6.8%)患者(3例男性;中位年龄64岁,范围43 - 87岁)在接受胸主动脉支架移植物修复后,中位20天(范围2 - 124天)发生了A型夹层,其中3例为B型夹层,1例为TAA,1例为创伤性夹层初次支架移植物修复后28个月出现的晚期I型内漏。
3例患者(2例夹层,1例内漏)中,近端支架移植物处主动脉壁撕裂导致逆行性A型夹层。另外2例患者(1例夹层,1例TAA)的A型夹层是由基础疾病引起的,与支架移植物无关。3例患者在支架移植物置入后3天、26天和124天接受了开放手术;2例手术成功,但第3例患者3个月后因多器官功能衰竭死亡。2例A型夹层未治疗:1例患者在成功通过支架移植物排除I型内漏后14天死于心脏压塞;另1例患者拒绝进一步治疗,存活下来。急性逆行性A型夹层后的手术相关死亡率为40%。
胸主动脉腔内支架移植物修复与手术修复相比,发病率和死亡率较低,尽管可能会发生急性或延迟性的潜在致命并发症。