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胸主动脉腔内支架移植物修复术后A型夹层。

Type A dissection following endovascular thoracic aortic stent-graft repair.

作者信息

Neuhauser Beate, Czermak Benedikt V, Fish John, Perkmann Reinhold, Jaschke Werner, Chemelli Andreas, Fraedrich Gustav

机构信息

Departments of Vascular Surgery, University Hospital Innsbruck, A-6020 Innsbruck, Austria.

出版信息

J Endovasc Ther. 2005 Feb;12(1):74-81. doi: 10.1583/04-1369.1.

Abstract

PURPOSE

To describe our experience with endovascular stent-graft repairs in the thoracic aorta focusing on the secondary complication of type A dissection.

METHODS

Between January 1996 and April 2004, 73 patients were treated for traumatic thoracic aortic rupture (n=15), type B dissection (n=22), or atherosclerotic descending thoracic aortic aneurysms (TAA, n=36). A retrospective review of the records found 5 (6.8%) patients (3 men; median age 64 years, range 43-87) who experienced a type A dissection at a median 20 days (range 2-124) after thoracic stent-graft repair for 3 type B dissections, 1 TAA, and a late type I endoleak that appeared 28 months after initial stent-graft repair of a traumatic dissection.

RESULTS

In 3 patients (2 dissections, 1 endoleak), a tear in the aortic wall at the proximal stent-graft was responsible for a retrograde type A dissection. Underlying disease was the cause of the type A dissection in the 2 other patients (1 dissection, 1 TAA) and was unrelated to the stent-grafts. Three patients underwent open surgery at 3, 26, and 124 days after stent-graft placement; 2 procedures were successful, but the third patient died 3 months later due to multiorgan failure. Two type A dissections were untreated: one patient died from cardiac tamponade 14 days after successful stent-graft exclusion of the type I endoleak; the other patient refused further treatment and survived. The procedure-related mortality following acute retrograde type A dissection was 40%.

CONCLUSIONS

Endovascular stent-graft repair of the thoracic aorta is associated with lower morbidity and mortality rates than surgical repair, although potentially lethal complications, acute or delayed, may occur.

摘要

目的

描述我们在胸主动脉腔内支架移植物修复方面的经验,重点关注A型夹层的继发性并发症。

方法

1996年1月至2004年4月期间,73例患者接受了创伤性胸主动脉破裂(n = 15)、B型夹层(n = 22)或动脉粥样硬化性降主动脉瘤(TAA,n = 36)的治疗。对记录进行回顾性分析发现,5例(6.8%)患者(3例男性;中位年龄64岁,范围43 - 87岁)在接受胸主动脉支架移植物修复后,中位20天(范围2 - 124天)发生了A型夹层,其中3例为B型夹层,1例为TAA,1例为创伤性夹层初次支架移植物修复后28个月出现的晚期I型内漏。

结果

3例患者(2例夹层,1例内漏)中,近端支架移植物处主动脉壁撕裂导致逆行性A型夹层。另外2例患者(1例夹层,1例TAA)的A型夹层是由基础疾病引起的,与支架移植物无关。3例患者在支架移植物置入后3天、26天和124天接受了开放手术;2例手术成功,但第3例患者3个月后因多器官功能衰竭死亡。2例A型夹层未治疗:1例患者在成功通过支架移植物排除I型内漏后14天死于心脏压塞;另1例患者拒绝进一步治疗,存活下来。急性逆行性A型夹层后的手术相关死亡率为40%。

结论

胸主动脉腔内支架移植物修复与手术修复相比,发病率和死亡率较低,尽管可能会发生急性或延迟性的潜在致命并发症。

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