Shah Aamir, Khoynezhad Ali
Division of Cardio-Thoracic Surgery, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Ann Cardiothorac Surg. 2016 Jul;5(4):389-96. doi: 10.21037/acs.2016.07.08.
Acute type A aortic dissection is a potentially lethal condition which requires immediate diagnostic and therapeutic intervention. Open surgical repair remains the standard of care as survival rates continue to improve in the modern surgical era. Unfortunately, up to twenty percent of patients are denied surgical therapy because they are deemed medically unfit to undergo open repair. The application of thoracic endovascular aortic repair (TEVAR) has changed the treatment paradigm for aortic disease involving the descending thoracic aorta and may be a viable rescue option for patients with type A dissection who are not eligible for open surgical repair. New endovascular devices and advanced image-guided procedures are continually evolving. This article summarizes the pathology of aortic dissection and focuses on currently available endovascular solutions for transapical and transfemoral stent graft deployment for acute aortic dissection involving the ascending aorta for selected patients who are ineligible for open surgical repair.
急性A型主动脉夹层是一种潜在的致命疾病,需要立即进行诊断和治疗干预。在现代外科时代,随着生存率不断提高,开放手术修复仍是治疗的金标准。不幸的是,高达20%的患者被拒绝手术治疗,因为他们被认为身体状况不适合接受开放修复。胸主动脉腔内修复术(TEVAR)的应用改变了降主动脉疾病的治疗模式,对于不适合开放手术修复的A型夹层患者,它可能是一种可行的挽救选择。新的血管内装置和先进的影像引导手术不断发展。本文总结了主动脉夹层的病理,并重点介绍了目前可用的血管内解决方案,即针对选定的不适合开放手术修复的升主动脉急性夹层患者,经心尖和经股动脉植入支架移植物。