Mills Shane J, Harrison Stephen A
Department of Medicine, Gastroenterology and Hepatology Service, Brooke Army Medical Center, 3851 Roger Brooke Drive, Fort Sam Houston, TX 78234-6200, USA.
Curr Gastroenterol Rep. 2005 Feb;7(1):32-6. doi: 10.1007/s11894-005-0063-4.
Fatty liver disease represents a common clinical entity. It is classically divided into alcoholic fatty liver disease (AFLD) and nonalcoholic fatty liver disease (NAFLD). Whereas AFLD occurs in as many as 10 million Americans, NAFLD represents the most common chronic liver disease and is the most common cause of liver enzyme abnormalities in the United States. Both diseases encompass the clinical spectrum of steatosis, steatohepatitis, and cirrhosis. Although they are histologically indistinct, AFLD and NAFLD follow different clinical courses. This article compares the natural history of these diseases.
脂肪性肝病是一种常见的临床病症。传统上它分为酒精性脂肪性肝病（AFLD）和非酒精性脂肪性肝病（NAFLD）。多达1000万美国人患有AFLD，而NAFLD是美国最常见的慢性肝病，也是肝酶异常最常见的原因。这两种疾病都涵盖了脂肪变性、脂肪性肝炎和肝硬化的临床谱。尽管它们在组织学上难以区分，但AFLD和NAFLD的临床病程不同。本文比较了这些疾病的自然史。
