Deiwick M, Hoffmeier A, Tjan T D T, Krasemann T, Schmid C, Scheld H H
Department of Thoracic and Cardiovascular Surgery, University Hospital Münster, Münster, Germany.
Thorac Cardiovasc Surg. 2005 Feb;53 Suppl 2:S135-40. doi: 10.1055/s-2004-830453.
The use of mechanical circulatory support for the treatment of heart failure in the pediatric population has become increasingly important in pediatric heart surgery units; however, the treatment options for the pediatric population have not attained the same level of technological development as we have seen for the adult population. The use of mechanical assistance as a bridge to transplantation or a bridge to recovery are the main indications for mechanical circulatory support in infants and children. The problem of organ donor shortage is even worse compared to the situation in the field of adult heart transplantations. Especially in Europe however, newly developed pulsatile, paracorporeal ventricular assist devices designed for long-term assist in children have demonstrated their ability to provide excellent results beyond the abilities of extracorporeal membrane oxygenation and centrifugal pumps, which are still the mainstay of mechanical support in children worldwide. Especially in the group of the smallest patients, the use of the most appropriate form of circulatory assistance has to be carefully considered as the co-incidence of respiratory failure as well as other complex physiological situations will severely influence the outcome.
在儿科心脏外科病房,使用机械循环支持治疗小儿心力衰竭变得越来越重要;然而,针对小儿群体的治疗方案尚未达到我们在成人群体中所看到的技术发展水平。将机械辅助作为移植桥梁或恢复桥梁是婴幼儿和儿童机械循环支持的主要适应症。与成人心脏移植领域的情况相比,器官供体短缺问题更为严重。然而,特别是在欧洲,新开发的用于儿童长期辅助的搏动性、体外心室辅助装置已证明,其能够提供超出体外膜肺氧合和离心泵能力的出色效果,而体外膜肺氧合和离心泵仍是全球儿童机械支持的主要手段。特别是在最小的患儿群体中,由于呼吸衰竭以及其他复杂生理状况的同时出现会严重影响治疗结果,因此必须仔细考虑使用最合适的循环辅助形式。