Fynn-Thompson Francis, Almond Christopher
Department of Cardiac Surgery, Childrens Hospital Boston, Harvard Medical School, 300 Longwood Avenue, Bader 273, Boston, MA 02115, USA.
Pediatr Cardiol. 2007 Mar-Apr;28(2):149-55. doi: 10.1007/s00246-006-1453-6. Epub 2007 Jan 29.
Ventricular assist device therapy is continuing to evolve in the practice of pediatric cardiac surgery. Although ECMO is still the most often applied mechanical support for infants and young children, a broader range of pulsatile, paracorporeal, as well as implantable ventricular assist devices are now available for pediatric application. A number of these innovative devices have been developed specifically for pediatric use with miniaturized pumps and optimized cannulas suitable for the entire age range of pediatric patients including neonates. Unlike ECMO, these devices can offer medium- to long-term support and have been successfully utilized as a bridge to transplant as well as a bridge to recovery. This review examines the different types of devices currently available, their clinical indications for use, future devices, and the current results of pediatric ventricular assist device therapy in the treatment of heart failure in the pediatric population.
心室辅助装置疗法在小儿心脏外科实践中不断发展。尽管体外膜肺氧合(ECMO)仍是婴幼儿最常用的机械支持手段,但现在有更广泛的搏动性、体外旁通以及可植入式心室辅助装置可供小儿使用。其中一些创新装置是专门为小儿设计的,配备了小型化泵和适合包括新生儿在内的各年龄段小儿患者的优化插管。与ECMO不同,这些装置可提供中长期支持,并已成功用作移植桥梁和康复桥梁。本综述探讨了目前可用的不同类型装置、其临床使用指征、未来的装置,以及小儿心室辅助装置疗法在治疗小儿心力衰竭方面的当前结果。