Brown Robert D, Flemming Kelly D, Meyer Fredric B, Cloft Harry J, Pollock Bruce E, Link Michael L
Department of Neurology, Mayo Clinic College of Medicine, Rochester, Minn 55905, USA.
Mayo Clin Proc. 2005 Feb;80(2):269-81. doi: 10.4065/80.2.269.
Intracranial vascular malformations are seen increasingly in clinical practice, primarily because of advances in cross-sectional brain and spinal cord imaging. Commonly encountered lesion types include arteriovenous malformations, cavernous malformations, venous malformations, dural arteriovenous fistulas, and capillary telangiectasias. Patients can experience various symptoms and signs at presentation. The natural history of vascular malformations depends on lesion type, location, size, and overall hemodynamics. The natural history for each lesion subtype is reviewed, with special consideration of the risk of hemorrhage or other adverse outcomes after the lesion is detected and any known predictors of hemorrhage or other outcomes. In practice, these data are compared with the risk of available treatment options as the optimal management is clarified. A multidisciplinary approach including neurosurgery, radiosurgery, interventional neuroradiology, and vascular neurology is most useful in determining the best management strategy.
颅内血管畸形在临床实践中越来越常见,主要是由于横断面脑和脊髓成像技术的进步。常见的病变类型包括动静脉畸形、海绵状畸形、静脉畸形、硬脑膜动静脉瘘和毛细血管扩张症。患者在就诊时可出现各种症状和体征。血管畸形的自然史取决于病变类型、位置、大小和整体血流动力学。本文回顾了每种病变亚型的自然史,特别考虑了病变被发现后出血或其他不良后果的风险以及任何已知的出血或其他后果的预测因素。在实际操作中,随着最佳治疗方案的明确,将这些数据与现有治疗选择的风险进行比较。包括神经外科、放射外科、介入神经放射学和血管神经病学在内的多学科方法对于确定最佳治疗策略最为有用。