Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Ann Clin Transl Neurol. 2021 Feb;8(2):504-522. doi: 10.1002/acn3.51277. Epub 2021 Jan 12.
CNS vascular malformation is an umbrella term that encompasses a wide variety of pathologies, with a wide range of therapeutic and diagnostic importance. This range spans lesions with a risk of devastating neurological compromise to lesions with a slow, static or benign course. Advances in neurovascular imaging along with increased utilization of these advances, have resulted in more frequent identification of these lesions. In this article, we provide an overview on definitions and classifications of CNS vascular malformations and outline the etiologic, diagnostic, prognostic, and therapeutic features for each entity. This review covers intracranial and spinal cord vascular malformations and discusses syndromes associated with CNS vascular malformations.
中枢神经系统血管畸形是一个涵盖广泛病理学的总称，具有广泛的治疗和诊断意义。这一范围包括了具有破坏性神经功能缺损风险的病变，以及具有缓慢、静态或良性病程的病变。神经血管成像技术的进步以及对这些技术的更多应用，导致了这些病变的更频繁发现。在本文中，我们提供了中枢神经系统血管畸形的定义和分类概述，并概述了每种病变的病因、诊断、预后和治疗特征。本综述涵盖了颅内和脊髓血管畸形，并讨论了与中枢神经系统血管畸形相关的综合征。
