Azathioprine-induced pancytopenia in a patient with pompholyx and deficiency of erythrocyte thiopurine methyltransferase.
作者信息
Konstantopoulou M, Belgi A, Griffiths K D, Seale J R C, Macfarlane A W
机构信息
Ysbyty Gwynedd, Bangor, Gwynedd LL57 2PW.
出版信息
BMJ. 2005 Feb 12;330(7487):350-1. doi: 10.1136/bmj.330.7487.350.
Abstract
摘要
相似文献
1
Azathioprine-induced pancytopenia in a patient with pompholyx and deficiency of erythrocyte thiopurine methyltransferase.硫唑嘌呤诱发的脓疱病患者全血细胞减少及红细胞硫嘌呤甲基转移酶缺乏
BMJ. 2005 Feb 12;330(7487):350-1. doi: 10.1136/bmj.330.7487.350.
2
Dosing azathioprine in thiopurine S-methyltransferase deficient inflammatory bowel disease patients.硫嘌呤甲基转移酶缺乏的炎症性肠病患者中硫唑嘌呤的给药
Gut. 2008 Jun;57(6):872. doi: 10.1136/gut.2007.145912.
3
4
Azathioprine-induced myelosuppression due to thiopurine methyltransferase deficiency in a patient with autoimmune hepatitis.一名自身免疫性肝炎患者因硫嘌呤甲基转移酶缺乏导致硫唑嘌呤引起的骨髓抑制。
J Hepatol. 1995 Sep;23(3):351-4. doi: 10.1016/0168-8278(95)80481-1.
5
Two cases of thiopurine methyltransferase (TPMT) deficiency--a lucky save and a near miss with azathioprine.两例硫嘌呤甲基转移酶（TPMT）缺乏症——使用硫唑嘌呤时一次幸运的挽救和一次险些酿成的大祸。
Br J Clin Pharmacol. 2006 Oct;62(4):473-6. doi: 10.1111/j.1365-2125.2005.02474.x.
6
Severe pancytopenia from thiopurine methyltransferase deficiency: a preventable complication of 6-mercaptopurine therapy in children with Crohn disease.硫嘌呤甲基转移酶缺乏导致的严重全血细胞减少：克罗恩病患儿接受6-巯基嘌呤治疗可预防的并发症
J Pediatr Gastroenterol Nutr. 2002 Nov;35(5):695-9. doi: 10.1097/00005176-200211000-00021.
7
Paradoxical elevated thiopurine S-methyltransferase activity after pancytopenia during azathioprine therapy: potential influence of red blood cell age.
Ther Drug Monit. 2008 Jun;30(3):390-3. doi: 10.1097/FTD.0b013e31816c20b3.
8
Azathioprine myelosuppression in multiple sclerosis: characterizing thiopurine methyltransferase polymorphisms.硫唑嘌呤在多发性硬化症中的骨髓抑制作用：硫嘌呤甲基转移酶多态性的特征分析
Mult Scler. 2006 Feb;12(1):108-11. doi: 10.1191/135248506ms1249cr.
9
Severe azathioprine-induced myelotoxicity in a kidney transplant patient with thiopurine S-methyltransferase-deficient genotype (TPMT*3A/*3C).硫嘌呤甲基转移酶缺陷基因型（TPMT*3A/*3C）的肾移植患者发生严重的硫唑嘌呤诱导的骨髓毒性。
Transpl Int. 2005 May;18(5):623-5. doi: 10.1111/j.1432-2277.2005.00095.x.
10
The Importance of Thiopurine S-Methyltransferase Gene Analysis Before Azathioprine Therapy.硫嘌呤甲基转移酶基因分析在硫唑嘌呤治疗前的重要性。
Clin Neuropharmacol. 2020 Jul/Aug;43(4):112-113. doi: 10.1097/WNF.0000000000000397.
引用本文的文献
1
Azathioprine-induced pancytopenia with normal TPMT activity presenting with HSV oral ulcers.硫唑嘌呤诱导的全血细胞减少伴正常硫嘌呤甲基转移酶活性，表现为单纯疱疹病毒口腔溃疡。
BMJ Case Rep. 2018 Jul 11;2018:bcr-2018-225209. doi: 10.1136/bcr-2018-225209.
2
Implementation of TPMT testing.硫嘌呤甲基转移酶（TPMT）检测的实施
Br J Clin Pharmacol. 2014 Apr;77(4):704-14. doi: 10.1111/bcp.12226.
3
Testing patients to allow tailored drug treatment.对患者进行检测以实现个性化药物治疗。
BMJ. 2005 Feb 12;330(7487):352. doi: 10.1136/bmj.330.7487.352.
本文引用的文献
1
Guidelines for prescribing azathioprine in dermatology.皮肤科硫唑嘌呤处方指南。
Br J Dermatol. 2004 Dec;151(6):1123-32. doi: 10.1111/j.1365-2133.2004.06323.x.
2
Guidelines for the management of pemphigus vulgaris.寻常型天疱疮管理指南。
Br J Dermatol. 2003 Nov;149(5):926-37. doi: 10.1111/j.1365-2133.2003.05665.x.
3
Determination of thiopurine S-methyltransferase activity in erythrocytes using 6-thioguanine as substrate and a non-extraction liquid chromatographic technique.使用6-硫鸟嘌呤作为底物和非萃取液相色谱技术测定红细胞中的硫嘌呤S-甲基转移酶活性。
J Chromatogr B Analyt Technol Biomed Life Sci. 2003 Dec 5;798(1):111-5. doi: 10.1016/j.jchromb.2003.09.017.
4
Azathioprine: current status and future considerations.
Int J Dermatol. 2003 May;42(5):335-41. doi: 10.1046/j.1365-4362.2003.01823.x.
5
Guidelines for the management of bullous pemphigoid.大疱性类天疱疮管理指南。
Br J Dermatol. 2002 Aug;147(2):214-21. doi: 10.1046/j.1365-2133.2002.04835.x.
6
Erythrocyte thiopurine methyl transferase assessment prior to azathioprine use in the UK.
QJM. 2002 Jul;95(7):439-44. doi: 10.1093/qjmed/95.7.439.
7
Azathioprine in dermatological practice. An overview with special emphasis on its use in non-bullous inflammatory dermatoses.
Adv Exp Med Biol. 1999;455:343-8.
8
Azathioprine in dermatology: a survey of current practice in the U.K.硫唑嘌呤在皮肤科的应用：英国当前实践调查
Br J Dermatol. 1997 Mar;136(3):351-5.
9
Thiopurine methyltransferase levels should be measured before commencing patients on azathioprine.
Br J Dermatol. 1997 Jan;136(1):133-4. doi: 10.1111/j.1365-2133.1997.tb08765.x.
Zotero 插件