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Azathioprine-induced pancytopenia in a patient with pompholyx and deficiency of erythrocyte thiopurine methyltransferase.

作者信息

Konstantopoulou M, Belgi A, Griffiths K D, Seale J R C, Macfarlane A W

机构信息

Ysbyty Gwynedd, Bangor, Gwynedd LL57 2PW.

出版信息

BMJ. 2005 Feb 12;330(7487):350-1. doi: 10.1136/bmj.330.7487.350.

DOI:10.1136/bmj.330.7487.350
PMID:15705694
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC548735/
Abstract
摘要

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引用本文的文献

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Azathioprine-induced pancytopenia with normal TPMT activity presenting with HSV oral ulcers.硫唑嘌呤诱导的全血细胞减少伴正常硫嘌呤甲基转移酶活性，表现为单纯疱疹病毒口腔溃疡。
BMJ Case Rep. 2018 Jul 11;2018:bcr-2018-225209. doi: 10.1136/bcr-2018-225209.
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Implementation of TPMT testing.硫嘌呤甲基转移酶（TPMT）检测的实施
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Testing patients to allow tailored drug treatment.对患者进行检测以实现个性化药物治疗。
BMJ. 2005 Feb 12;330(7487):352. doi: 10.1136/bmj.330.7487.352.

本文引用的文献

1
Guidelines for prescribing azathioprine in dermatology.皮肤科硫唑嘌呤处方指南。
Br J Dermatol. 2004 Dec;151(6):1123-32. doi: 10.1111/j.1365-2133.2004.06323.x.
2
Guidelines for the management of pemphigus vulgaris.寻常型天疱疮管理指南。
Br J Dermatol. 2003 Nov;149(5):926-37. doi: 10.1111/j.1365-2133.2003.05665.x.
3
Determination of thiopurine S-methyltransferase activity in erythrocytes using 6-thioguanine as substrate and a non-extraction liquid chromatographic technique.使用6-硫鸟嘌呤作为底物和非萃取液相色谱技术测定红细胞中的硫嘌呤S-甲基转移酶活性。
J Chromatogr B Analyt Technol Biomed Life Sci. 2003 Dec 5;798(1):111-5. doi: 10.1016/j.jchromb.2003.09.017.
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Azathioprine: current status and future considerations.
Int J Dermatol. 2003 May;42(5):335-41. doi: 10.1046/j.1365-4362.2003.01823.x.
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Guidelines for the management of bullous pemphigoid.大疱性类天疱疮管理指南。
Br J Dermatol. 2002 Aug;147(2):214-21. doi: 10.1046/j.1365-2133.2002.04835.x.
6
Erythrocyte thiopurine methyl transferase assessment prior to azathioprine use in the UK.
QJM. 2002 Jul;95(7):439-44. doi: 10.1093/qjmed/95.7.439.
7
Azathioprine in dermatological practice. An overview with special emphasis on its use in non-bullous inflammatory dermatoses.
Adv Exp Med Biol. 1999;455:343-8.
8
Azathioprine in dermatology: a survey of current practice in the U.K.硫唑嘌呤在皮肤科的应用：英国当前实践调查
Br J Dermatol. 1997 Mar;136(3):351-5.
9
Thiopurine methyltransferase levels should be measured before commencing patients on azathioprine.
Br J Dermatol. 1997 Jan;136(1):133-4. doi: 10.1111/j.1365-2133.1997.tb08765.x.
10
The role of genetic variation in thiopurine methyltransferase activity and the efficacy and/or side effects of azathioprine therapy in dermatologic patients.基因变异在硫嘌呤甲基转移酶活性以及皮肤病患者硫唑嘌呤治疗的疗效和/或副作用中的作用。
Arch Dermatol. 1995 Feb;131(2):193-7.