[来自红瑶长梗唇柱苣苔茎的苯乙醇苷类化合物]
[Phenylethanoid glycosides from stem of Chirita longgangensis var. hongyao].
作者信息
Wang Man-Yuan, Yang Lan, Tu You-You
机构信息
Institute of Chinese Materia Medica, China Academy of Traditional Chinese Medicine, Beijing 100700, China.
出版信息
Zhongguo Zhong Yao Za Zhi. 2005 Dec;30(24):1921-3.
OBJECTIVE
To isolate and elucidate the constituents from stem of Chirita longgangensis var. hongyao.
METHOD
The constituents were extracted with methanol and isolated by chromatography on silica gel, Sephadex LH-20 and ODS. The structures were determined by NMR and MS spectral analysis.
RESULT
Five phenylethanoid glycosides were identified as 3, 4-dihydroxyphenyl alcohol-beta-D-glucopyranoside (1), 3, 4-dihydroxyphenyl alcohol-6-O-caffeoyl--D-glucopyranoside (calceolarioside B) (2), 3, 4-dihydroxyphenyl alcohol-beta-D-glucopyranosyl-(1 --> 3)-6-O-caffeoyl-beta-D-glucopyranoside (plantainoside D) (3), 3, 4-dihydroxyphenyl alcohol-beta-D-glucopyranosyl-(1 --> 3)-4-O-caffeoyl-beta-D-glucopyranoside (plantamajoside) (4), 3, 4-dihydroxyphenyl alcohol-beta-D-glucopyranosyl-(1 --> 3)-6-O-feruloyl-beta-D-glucopyranoside (scroside E) (5), respectively.
CONCLUSION
Compounds 3 and 5 were isolated for the first time from the family Gesneriaceae, and compounds 1, 2 and 4 were isolated for the first time from the genus Chirita.
目的
从红瑶长蒴苣苔茎中分离并阐明其成分。
方法
用甲醇提取成分，通过硅胶柱色谱、葡聚糖凝胶LH - 20柱色谱和ODS柱色谱进行分离。通过核磁共振（NMR）和质谱（MS）光谱分析确定结构。
结果
鉴定出5种苯乙醇苷，分别为3,4 - 二羟基苯甲醇 - β - D - 吡喃葡萄糖苷（1）、3,4 - 二羟基苯甲醇 - 6 - O - 咖啡酰基 - β - D - 吡喃葡萄糖苷（洋地黄叶苷B）（2）、3,4 - 二羟基苯甲醇 - β - D - 吡喃葡萄糖基 - (1→3) - 6 - O - 咖啡酰基 - β - D - 吡喃葡萄糖苷（车前苷D）（3）、3,4 - 二羟基苯甲醇 - β - D - 吡喃葡萄糖基 - (1→3) - 4 - O - 咖啡酰基 - β - D - 吡喃葡萄糖苷（大车前苷）（4）、3,4 - 二羟基苯甲醇 - β - D - 吡喃葡萄糖基 - (1→3) - 6 - O - 阿魏酰基 - β - D - 吡喃葡萄糖苷（苦苣苔苷E）（5）。
结论
化合物3和5首次从苦苣苔科植物中分离得到，化合物1、2和4首次从长蒴苣苔属植物中分离得到。
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