Zou Lian-Chun, Zhu Tong-Fei, Xiang Hua, Yu Lu, Yan Zhi-Hui, Gan Shu-Cai, Wang Da-Cheng, Zeng Sheng, Deng Xu-Ming
College of Chemistry, Jilin University, Changchun 130062, P.R. China.
Molecules. 2008 Sep 1;13(9):2049-57. doi: 10.3390/molecules13092049.
Three new secoiridoid glycosides, named picrogentiosides A (1), B (2) and C (3), have been isolated from the underground parts of Picrorhiza Scrophulariiflora, together with the two known compounds plantamajoside (4) and plantainoside D (5). Their structures were established by spectroscopic analyses and comparisons with data from related compounds. A pilot pharmacological study showed that picrogentiosides A (1) and B (2) have an immunomodulatory effect in vitro.
从胡黄连的地下部分分离出了三种新的裂环烯醚萜苷，分别命名为苦味胡黄连苷A（1）、B（2）和C（3），同时还分离出了两种已知化合物大车前苷（4）和车前糖苷D（5）。通过光谱分析并与相关化合物的数据进行比较确定了它们的结构。一项初步药理研究表明，苦味胡黄连苷A（1）和B（2）在体外具有免疫调节作用。
