Yamaguchi-Shinozaki Kazuko, Shinozaki Kazuo
Laboratory of Plant Molecular Physiology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
Trends Plant Sci. 2005 Feb;10(2):88-94. doi: 10.1016/j.tplants.2004.12.012.
cis-Acting regulatory elements are important molecular switches involved in the transcriptional regulation of a dynamic network of gene activities controlling various biological processes, including abiotic stress responses, hormone responses and developmental processes. In particular, understanding regulatory gene networks in stress response cascades depends on successful functional analyses of cis-acting elements. The ever-improving accuracy of transcriptome expression profiling has led to the identification of various combinations of cis-acting elements in the promoter regions of stress-inducible genes involved in stress and hormone responses. Here we discuss major cis-acting elements, such as the ABA-responsive element (ABRE) and the dehydration-responsive element/C-repeat (DRE/CRT), that are a vital part of ABA-dependent and ABA-independent gene expression in osmotic and cold stress responses.
顺式作用调控元件是重要的分子开关，参与控制各种生物过程（包括非生物胁迫响应、激素响应和发育过程）的基因活性动态网络的转录调控。特别是，理解应激反应级联中的调控基因网络依赖于顺式作用元件的成功功能分析。转录组表达谱分析准确性的不断提高，已导致在参与胁迫和激素响应的胁迫诱导基因的启动子区域中鉴定出各种顺式作用元件组合。在这里，我们讨论主要的顺式作用元件，如脱落酸应答元件（ABRE）和脱水应答元件/C重复序列（DRE/CRT），它们是渗透胁迫和冷胁迫响应中依赖脱落酸和不依赖脱落酸基因表达的重要组成部分。
