Evans Karen, Costabile Raymond A
47th Combat Support Hospital, Fort Lewis, Washington, USA.
J Urol. 2005 Mar;173(3):858-61. doi: 10.1097/01.ju.0000152578.07262.1c.
While seasonal variation of stone disease is well described, the time to formation of urinary calculi is unknown. Because southwestern Asia is a high risk environment for stone disease, the date of entry into this region is a definitive beginning to a period of increased risk of urinary calculi. The recent influx of Department of Defense personnel into southwestern Asia provided the opportunity to observe stone disease in a cohort of healthy personnel during a well-defined period of increased risk of stone formation.
A database was constructed for all patients presenting with symptomatic urinary calculi to a single military hospital deployed to Kuwait from March through August 2003. Patient demographics, stone characteristics and time to formation of symptomatic urinary calculi were evaluated.
A total of 182 patients were diagnosed with 218 symptomatic stones. Mean time to formation of symptomatic urinary calculi was 93 days with a standard deviation of 42 days.
This study provides unprecedented information about the development of symptomatic urinary calculi in a high risk environment. While unique aspects of the population, environment and medical system created a singular opportunity to study stone disease, the results of this study are applicable to the general population.
虽然结石病的季节性变化已有充分描述,但尿结石形成的时间尚不清楚。由于亚洲西南部是结石病的高风险地区,进入该地区的日期是尿结石风险增加期的明确起点。最近美国国防部人员涌入亚洲西南部,为观察一群健康人员在明确的结石形成风险增加期内的结石病情况提供了机会。
构建了一个数据库,纳入2003年3月至8月部署在科威特的一家军事医院中所有出现有症状尿结石的患者。对患者的人口统计学特征、结石特征以及有症状尿结石的形成时间进行了评估。
共有182例患者被诊断出患有218颗有症状的结石。有症状尿结石形成的平均时间为93天,标准差为42天。
本研究提供了关于高风险环境中有症状尿结石发展情况的前所未有的信息。虽然人群、环境和医疗系统的独特方面创造了研究结石病的独特机会,但本研究结果适用于一般人群。