Walker Woodruff J, McDowell Simon J
Department of Radiology, The Royal Surrey County Hospital, Guildford, UK.
Am J Obstet Gynecol. 2006 Nov;195(5):1266-71. doi: 10.1016/j.ajog.2006.04.011. Epub 2006 Jun 21.
This study was undertaken to evaluate the incidence and outcome of pregnancies after uterine artery embolization (UAE) for symptomatic uterine fibroids.
A retrospective analysis of all pregnancies after UAE by a single interventional radiologist.
Fifty-six completed pregnancies were identified in approximately 1200 women after UAE. One hundred eight patients were attempting to become pregnant and 33 of these became pregnant. Thirty-three (58.9%) of the 56 pregnancies had successful outcomes. Six (18.2%) of these were premature. Seventeen (30.4%) pregnancies miscarried. There were 3 terminations, 2 stillbirths, and 1 ectopic pregnancy. Of the 33 deliveries, 24 (72.7%) were delivered by cesarean section. There were 13 elective sections and the indication for 9 was fibroids. There were 6 cases of postpartum hemorrhage (18.2%).
Compared with the general obstetric population, there is a significant increase in delivery by cesarean section and an increase in preterm delivery, postpartum hemorrhage, miscarriage, and lower pregnancy rates. When taking into account the demographics of the study population, these results can be partly explained. There were no other obstetric risk identified.
本研究旨在评估因症状性子宫肌瘤接受子宫动脉栓塞术(UAE)后妊娠的发生率及结局。
由一名介入放射科医生对UAE术后的所有妊娠情况进行回顾性分析。
在约1200名接受UAE的女性中,共识别出56例足月妊娠。108名患者尝试怀孕,其中33名成功受孕。56例妊娠中,33例(58.9%)结局良好。其中6例(18.2%)早产。17例(30.4%)妊娠流产。有3例终止妊娠、2例死产和1例异位妊娠。33例分娩中,24例(72.7%)通过剖宫产分娩。其中13例为选择性剖宫产,9例的指征为子宫肌瘤。有6例产后出血(18.2%)。
与普通产科人群相比,剖宫产分娩率显著增加,早产、产后出血、流产率升高,妊娠率降低。考虑到研究人群的人口统计学特征,这些结果可以得到部分解释。未发现其他产科风险。