Holub Zdenek, Mara Michal, Kuzel David, Jabor Antonin, Maskova Jana, Eim Josef
Department of Obstetrics and Gynecology, Baby Friendly Hospital, Kladno, Czech Republic.
Fertil Steril. 2008 Nov;90(5):1886-91. doi: 10.1016/j.fertnstert.2007.08.033. Epub 2007 Dec 26.
To assess the reproductive outcomes after laparoscopic uterine artery occlusion (LUAO) and uterine artery embolization (UAE) in women with symptomatic fibroids.
Prospective, clinical multicentric study.
Endoscopic center in the department of obstetrics and gynecology at a hospital in the Czech Republic.
PATIENT(S): Thirty-eight pregnant women after LUAO and 20 pregnant women after UAE.
INTERVENTION(S): Laparoscopic uterine artery occlusion and UAE.
MAIN OUTCOME MEASURE(S): Pregnancy, abortion, preterm delivery, and live-birth rates.
RESULT(S): Pregnancies after uterine embolization had a statistically significantly higher rate for spontaneous abortion (56%) than did pregnancies after surgical uterine artery occlusion (10.5%). The risk of malpresentation (20%) and the rate for cesarean section (80%) after UAE similarly were higher than was the risk after laparoscopic occlusion; however, these differences were not statistically significant. Also, there were no significant differences between the groups in preterm deliveries (15.3% in the LUAO group vs. 20% in the UAE group).
CONCLUSION(S): Pregnancies of women who were treated with uterine embolization were at significantly increased risk for spontaneous abortion when compared with pregnancies of women treated with LUAO.
评估有症状子宫肌瘤患者行腹腔镜子宫动脉阻断术（LUAO）和子宫动脉栓塞术（UAE）后的生殖结局。
前瞻性临床多中心研究。
捷克共和国一家医院妇产科的内镜中心。
38例行LUAO术后的孕妇和20例行UAE术后的孕妇。
腹腔镜子宫动脉阻断术和子宫动脉栓塞术。
妊娠、流产、早产和活产率。
子宫栓塞术后妊娠的自然流产率（56%）在统计学上显著高于手术子宫动脉阻断术后妊娠的自然流产率（10.5%）。UAE术后胎位异常风险（20%）和剖宫产率（80%）同样高于腹腔镜阻断术后的风险；然而，这些差异无统计学意义。此外，两组间早产率无显著差异（LUAO组为15.3%，UAE组为20%）。
与接受LUAO治疗的女性妊娠相比，接受子宫栓塞术治疗的女性妊娠自然流产风险显著增加。
