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胎儿神经移植影响下的深染宿主神经元超微结构的恢复

The recovery of the ultrastructure of hyperchromic host neurons under the influence of fetal neurotransplants.

作者信息

Kleshchinov V N, Alexandrova M

机构信息

Laboratory of Experimental Neurogenetics, N.I. Vavilov Institute of General Genetics, USSR Academy of Sciences, Moscow.

出版信息

J Neural Transplant Plast. 1992 Jan-Mar;3(1):51-61. doi: 10.1155/NP.1992.51.

DOI:10.1155/NP.1992.51
PMID:1571399
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2565132/
Abstract

Fetal neocortical transplants placed into a previously prepared cavity in the cortex of adult animals inhibited destructive processes in host neurons surrounding the place of injury. This was demonstrated by a gradual reduction in the number of hyperchromic and shrunken host neurons and the recovery of the ultrastructure of dystrophic cells which die as a result of neuronophagia or sclerosis in the absence of the transplants.

摘要

植入成年动物皮质预先准备好的腔隙中的胎儿新皮质移植体,抑制了损伤部位周围宿主神经元的破坏过程。这表现为宿主神经元中核染色质增多和皱缩的数量逐渐减少,以及在没有移植体时因噬神经元作用或硬化而死亡的营养不良细胞超微结构的恢复。