Damas J, Volon G
C R Seances Soc Biol Fil. 1978;172(6):1250-3.
The hypotensive activity of arachidonic acid is more important by intraaortic than by intravenous injection, in the rat. The evisceration of the animal abolishes this difference and reduces the activity of arachidonic acid. This action is not accompanied by thrombopenia and is only observed with high doses of arachidonic acid in this species. The hypotensive activity is inhibited by indomethacin but not by tranylcypromine.
在大鼠中，花生四烯酸的降压活性通过主动脉内注射比静脉注射更为显著。动物去内脏后消除了这种差异，并降低了花生四烯酸的活性。这种作用不伴有血小板减少，且仅在该物种中高剂量的花生四烯酸时才观察到。消炎痛可抑制其降压活性，但反苯环丙胺则不能。
