Cho Sang Hyun, Vassiliev Oleg N, Lee Seungsoo, Liu H Helen, Ibbott Geoffrey S, Mohan Radhe
Department of Radiation Physics, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA.
Med Phys. 2005 Jan;32(1):137-48. doi: 10.1118/1.1829172.
The current study presents the reference photon dosimetry data (RPDD) and reference phase space data (RPSD) for the 6 MV photon beam from Varian 2100 series linear accelerators. The RPDD provide the basic photon dosimetry data, typically collected during the initial commissioning of a new linear accelerator, including output factors, depth dose data, and beam profile data in air and in water. The RPSD provide the full phase space information, such as position, direction, and energy for each particle generated inside the head of any particular linear accelerator in question. The dosimetric characteristics if the 6 MV photon beam from the majority of the aforementioned accelerators, which are unaltered from the manufacturer's original specifications, can be fully described with these two data sets within a clinically acceptable uncertainty (approximately +/-2 %). The current study also presents a detailed procedure to establish the RPDD and RPSD using measured data and Monte Carlo calculations. The RPDD were constructed by compiling our own measured data and the average data based on the analysis of more than 50 sets of measured data from the Radiological Physics Center (RPC) and 10 sets of clinical dosimetry data obtained from 10 different institutions participating in the RPC's quality assurance monitoring program. All the measured data from the RPC and the RPC-monitored institutions were found to be within a statistically tight range (i.e., 1sigma approximately 1% or less) for each dosimetric quantity. The manufacturer's standard data, except for in-air off-axis factors that are available only from the current study, were compared with the RPDD, showing that the manufacturer's standard data could also be used as the RPDD for the photon beam studied in this study. The RPSD were obtained from Monte Carlo calculations using the BEAMnrc/ DOSXYZnrc code system with 6.2 MeV (a spread of 3% full width at half maximum) and 1.0 mm full width at half maximum as the values of the energy and radial spread of a Gaussian electron pencil beam incident on the target, respectively. The RPSD were capable of generating Monte Carlo data that agreed with the RPDD within the acceptance criteria adopted in the current study (e.g., 1% or 1 mm for depth dose). A complete set of the RPDD and RPSD from the current study is available from the RPC website (http://rpc.mdanderson.org) or via mass storage media such as DVD or CD-ROM upon request.
本研究给出了瓦里安2100系列直线加速器6兆伏光子束的参考光子剂量学数据(RPDD)和参考相空间数据(RPSD)。RPDD提供基本的光子剂量学数据,通常是在新直线加速器初始调试期间收集的,包括输出因子、深度剂量数据以及空气中和水中的射野数据。RPSD提供完整的相空间信息,例如所讨论的任何特定直线加速器机头内产生的每个粒子的位置、方向和能量。上述大多数加速器的6兆伏光子束的剂量学特性,与制造商的原始规格相比未发生改变,可通过这两组数据集在临床可接受的不确定度(约±2%)范围内进行全面描述。本研究还给出了一个使用测量数据和蒙特卡罗计算来建立RPDD和RPSD的详细程序。RPDD是通过汇编我们自己的测量数据以及基于对放射物理中心(RPC)50多组测量数据和从参与RPC质量保证监测计划的10个不同机构获得的10组临床剂量学数据的分析得出的平均数据构建而成。发现RPC和RPC监测机构的所有测量数据对于每个剂量学量都在统计上的紧密范围内(即1σ约为1%或更小)。将制造商的标准数据与RPDD进行了比较,结果表明,除了仅在本研究中可获得的空气中离轴因子外,制造商的标准数据也可作为本研究中所研究光子束的RPDD。RPSD是使用BEAMnrc/DOSXYZnrc代码系统通过蒙特卡罗计算获得的,其中高斯电子笔形束入射到靶上的能量值为6.2兆伏(半高宽展宽3%),径向展宽值为半高宽1.0毫米。RPSD能够生成与本研究采用的验收标准(例如深度剂量为1%或1毫米)内的RPDD一致的蒙特卡罗数据。本研究完整的RPDD和RPSD集可从RPC网站(http://rpc.mdanderson.org)获取,或应要求通过DVD或CD-ROM等大容量存储介质获取。