Schroeter Careen A, Pleunis Judith, van Nispen tot Pannerden Claire, Reineke Thorsten, Neumann Herman A M
Department of Laser Therapy, Medical Centre Maastricht, Maastricht, The Netherlands.
Dermatol Surg. 2005 Jan;31(1):71-5. doi: 10.1111/j.1524-4725.2005.31011.
Plantar wart treatment remains a challenging one. Various treatment modalities have been previously used and are still in current use. The problem remains in the degree of response to these treatments and the side effects associated with them.
The aim of this study was to test a new treatment modality for therapy-resistant plantar warts.
Thirty-one patients with 48 plantar warts were randomly selected from the Department of Laser Therapy, Medical Centre Maastricht, The Netherlands. The mean age of the patients was 29 years (range 6-74 years). The mean incubation time was 6.8 hours, and the mean treatment time was 18.7 minutes per wart. Each wart was treated an average of 2.3 times, with a median fluence of 100 cm2.
Forty-two of 48 (88%) warts showed a complete response. A trend was found between total clearance and size of the warts, age of the patient, and the mean treatment time. No significant side effects were seen postoperatively.
This study showed that recalcitrant plantar warts were successfully treated with no significant side effects; however, the user needs sufficient experience for this new effective treatment application.
跖疣的治疗仍然具有挑战性。以前已经使用过多种治疗方式，并且目前仍在使用。问题仍然在于对这些治疗的反应程度以及与之相关的副作用。
本研究的目的是测试一种针对治疗抵抗性跖疣的新治疗方式。
从荷兰马斯特里赫特医学中心激光治疗科随机选取31例患有48个跖疣的患者。患者的平均年龄为29岁（范围6 - 74岁）。平均孵育时间为6.8小时，每个疣体的平均治疗时间为18.7分钟。每个疣体平均接受2.3次治疗，中位能量密度为100 cm²。
48个疣体中的42个（88%）显示完全缓解。在完全清除与疣体大小、患者年龄和平均治疗时间之间发现了一种趋势。术后未观察到明显的副作用。
本研究表明，顽固性跖疣得到了成功治疗，且无明显副作用；然而，使用者需要足够的经验来应用这种新的有效治疗方法。
