Schwarz B, Bischof H P, Kunze M
Institut für Sozialmedizin, University Vienna, Austria.
Eur J Epidemiol. 1992 Jan;8(1):40-7. doi: 10.1007/BF02427390.
We investigated mean levels and prevalences of total cholesterol, HDL cholesterol, triglycerides, fasting blood glucose, systolic blood pressure and body mass index in adults aged 25 to 64 years participating in the WHO Country-wide Integrated Noncommunicable Diseases Intervention (CINDI) Programme in Vorarlberg, western Austria. According to the Austrian expert panel and based upon the above age standardized risk factors 50.9% of the male and 29.3% of the female population were at high risk for developing coronary heart disease. Risk factor levels were further compared between euglycemic and hyperglycemic participants. After adjusting for age hyperglycemia was associated with higher body mass index in men (p = 0.026) and women (p less than 0.001), higher systolic blood pressure in men (p less than 0.001) and women (p = 0.003), and higher levels of triglycerides in women (p = 0.008). No significant differences were observed in total and HDL cholesterol in either sex. When controlling for age and body mass index, fasting blood glucose levels had significant associations only with systolic blood pressure in men (p = 0.001). But, with respect to all risk factors, hyperglycemic participants had an age-adjusted adverse coronary risk profile both in men (p = 0.002) and in women (p less than 0.001).
我们调查了参与奥地利西部福拉尔贝格州世界卫生组织全国非传染性疾病综合干预（CINDI）项目的25至64岁成年人的总胆固醇、高密度脂蛋白胆固醇、甘油三酯、空腹血糖、收缩压和体重指数的平均水平及患病率。根据奥地利专家小组的意见，并基于上述年龄标准化风险因素，50.9%的男性和29.3%的女性人群有患冠心病的高风险。对血糖正常和血糖过高的参与者的风险因素水平进行了进一步比较。在调整年龄后，高血糖与男性（p = 0.026）和女性（p < 0.001）较高的体重指数、男性（p < 0.001）和女性（p = 0.003）较高的收缩压以及女性较高的甘油三酯水平（p = 0.008）相关。在总胆固醇和高密度脂蛋白胆固醇方面，两性均未观察到显著差异。在控制年龄和体重指数后，空腹血糖水平仅与男性的收缩压有显著关联（p = 0.001）。但是，就所有风险因素而言，血糖过高的参与者在男性（p = 0.002）和女性（p < 0.001）中均有年龄调整后的不良冠心病风险状况。
