Marczinski Cecile A, Fillmore Mark T
Department of Psychology, University of Kentucky, Lexington, KY 40506-0044, USA.
Exp Clin Psychopharmacol. 2005 Feb;13(1):15-24. doi: 10.1037/1064-1297.13.1.15.
This study examined the effects of alcohol on the ability to execute and inhibit behavior in a context in which preliminary information signaled the likelihood that a response should be executed or suppressed. Adults (N = 24) performed a cued go/no-go task that required quick responses to go targets and suppression of responses to no-go targets. Cue dependency was manipulated by varying the predictive validity of the cues, and performance was tested under 3 doses of alcohol: 0.00 g/kg, 0.45 g/kg, and 0.65 g/kg. Dose-dependent increases in cue dependence were only observed with highly predictive cues. Results suggest that alcohol-induced increases in stimulus control over behavior might be most likely in situations when stimulus control over behavior has already been established.
本研究考察了在初步信息表明应执行或抑制反应的可能性的情境中,酒精对行为执行和抑制能力的影响。成年人(N = 24)进行了一项线索提示的“去/不去”任务,该任务要求对“去”目标快速做出反应,并抑制对“不去”目标的反应。通过改变线索的预测有效性来操纵线索依赖性,并在三种酒精剂量下测试表现:0.00 g/kg、0.45 g/kg和0.65 g/kg。仅在具有高度预测性的线索中观察到线索依赖性的剂量依赖性增加。结果表明,在行为的刺激控制已经建立的情况下,酒精引起的对行为的刺激控制增加可能最为明显。