Kreiborg S, Cohen M M
Department of Pediatric Dentistry, Royal Dental College, Copenhagen, Denmark.
J Craniofac Genet Dev Biol. 1992 Jan-Mar;12(1):41-8.
As part of an ongoing study of 119 patients with the Apert syndrome, extensive data were available for the analysis of oral manifestations, including mouth shape, lip posture, palatal morphology, dental anomalies, and malocclusion. Findings included a characteristic trapezoidal-shaped mouth. Cleft soft palate or bifid uvula was found in approximately 75%. A Byzantine-arch shaped palate was recorded in almost all patients. Dental anomalies included severely delayed eruption, ectopic eruption, and shovel-shaped incisors. Malocclusion tended to be severe with mesial molar occlusion, mandibular overjet, anterior and posterior crossbites, and severe crowding of teeth. The oral manifestations of Apert syndrome are compared and contrasted with those of Crouzon syndrome.
作为一项对119例Apert综合征患者进行的正在进行的研究的一部分，有大量数据可用于分析口腔表现，包括口形、唇姿势、腭形态、牙齿异常和错牙合。研究结果包括特征性的梯形口。约75%的患者存在软腭裂或悬雍垂裂。几乎所有患者均记录到拜占庭拱形腭。牙齿异常包括严重的萌出延迟、异位萌出和铲形切牙。错牙合往往较为严重，表现为近中磨牙咬合、下颌前突、前后牙反牙合以及严重的牙齿拥挤。将Apert综合征的口腔表现与Crouzon综合征的口腔表现进行了比较和对比。
