Arboix Adrià, García-Plata Cristòbal, García-Eroles Luis, Massons Joan, Comes Emili, Oliveres Montserrat, Targa Cecilia
Cerebrovascular Division, Dept. of Neurology, Hospital Universitari del Sagrat Cor, Universitat de Barcelona, Viladomat 288, 08029 Barcelona, Spain.
J Neurol. 2005 Feb;252(2):156-62. doi: 10.1007/s00415-005-0622-5.
We report a clinical description of pure sensory stroke based on data collected from a prospective acute stroke registry.
From 2500 acute stroke patients included in a hospital-based prospective stroke registry over a 12-year period, 99 were identified as having pure sensory stroke.
Pure sensory stroke accounted for 4.7% of all acute stroke patients, 5.4% of acute ischemic stroke, and 17.4% of lacunar syndromes. Complete hemisensory syndrome was present in 80 patients and incomplete hemisensory syndrome in 19 (cheiro-oral syndrome 12, cheiro-oral-pedal 6, isolated oral syndrome 1). The lacunar hypothesis was fulfilled in 88% of patients. Atherothrombotic infarction occurred in 8 patients, intracerebral hemorrhage in 3, and stroke of undetermined cause in 1. Hemorrhagic pure sensory stroke was diagnosed in 1% of all cases of hemorrhagic stroke (n = 270) in the database. Outcome was good (in-hospital mortality 0%, symptom-free at discharge 41.5%). After multivariate analysis, absence of disability at discharge, hypertension, diabetes, hyperlipidemia, and thalamic (56.5%) and corona radiata (4%) locations were clinical and topographic variables significantly associated with pure sensory stroke.
Pure sensory stroke is an infrequent cerebrovascular syndrome, in which the lacunar hypothesis is supported. Most patients had thalamic lacunar infarction. Incomplete hemisensory syndromes were also caused by a lacunar infarct in 84% of patients. Hemorrhagic pure sensory stroke accounted only for 3% of the cases. The prognosis is good with striking similarity to other lacunar strokes. There are important differences between pure sensory stroke and nonlacunar strokes.
基于从前瞻性急性卒中登记处收集的数据，报告纯感觉性卒中的临床描述。
在一项为期12年的基于医院的前瞻性卒中登记研究纳入的2500例急性卒中患者中，99例被确定为患有纯感觉性卒中。
纯感觉性卒中占所有急性卒中患者的4.7%，急性缺血性卒中的5.4%，腔隙综合征的17.4%。80例患者出现完全性偏身感觉综合征，19例出现不完全性偏身感觉综合征（口-手综合征12例，口-手-足综合征6例，孤立性口部综合征1例）。88%的患者符合腔隙性假说。8例发生动脉粥样硬化性血栓形成性梗死，3例发生脑出血，1例病因不明。在数据库中所有出血性卒中病例（n = 270）中，1%被诊断为出血性纯感觉性卒中。预后良好（住院死亡率0%，出院时无症状41.5%）。多因素分析后，出院时无残疾、高血压、糖尿病、高脂血症以及丘脑（56.5%）和放射冠（4%）部位是与纯感觉性卒中显著相关的临床和地形学变量。
纯感觉性卒中是一种罕见的脑血管综合征，腔隙性假说得到支持。大多数患者有丘脑腔隙性梗死。84%的患者不完全性偏身感觉综合征也由腔隙性梗死引起。出血性纯感觉性卒中仅占病例的3%。预后良好，与其他腔隙性卒中极为相似。纯感觉性卒中和非腔隙性卒中之间存在重要差异。
