Jiang Youli, Xiong Yao, Chi Yue, Lin Fu, Zhao Qingshi, Li Yanfeng
Department of Neurology, People's Hospital of Longhua, Shenzhen, 518109, People's Republic of China.
Risk Manag Healthc Policy. 2024 Jan 18;17:191-204. doi: 10.2147/RMHP.S445001. eCollection 2024.
Timely medical attention is crucial for patients with Acute Ischemic Stroke (AIS), as delays can significantly impact therapeutic outcomes. These delays are influenced by a combination of socio-cultural, educational, and clinical factors.
An in-depth analysis was conducted to assess the prevalence and median duration of healthcare-seeking delays in AIS patients. The study specifically investigated the independent impacts of sociocultural and clinical determinants on these delays, with a focus on immigrant status, gender disparities, and educational levels. Multivariate regression analysis was employed to identify these independent effects while controlling for potential confounding factors.
Among 1419 AIS patients, 82.52% (n = 1171) experienced delays exceeding 2 hours from symptom onset of symptoms to hospital arrival. The median delay was 12.3 hours. Immigrant populations encountering longer delays compared to native groups. Younger males (<45 years) and elderly females were more prone to delay in healthcare-seeking. Identified independent risk factors for delay included male gender (OR = 1.65 [95% CI:1.14-2.48]), self-acknowledged diabetes (OR = 2.50 [95% CI:1.21-5.17]), small vessel (OR = 2.07 [95% CI:1.27-3.36]), and wake stroke (OR = 7.04 [95% CI:3.69-13.44]). Educational background (high school and above), GCS score with 3-8 points (OR = 0.52 [95% CI:0.09-0.69]), understanding stroke-related knowledge (OR = 0.26 [95% CI:0.09-0.44]), conscious disturbance (OR = 0.25 [95% CI:0.10-0.62]) and limb weakness (OR=0.21[95% CI:0.21-0.49]) are protective factors for timely treatment.
Immigrant populations experienced longer delays from symptom onset to hospital arrival. The crucial roles of education and knowledge about stroke underscore the need for enhanced health literacy campaigns and public awareness, with a targeted focus on younger males and elderly females.
对于急性缺血性卒中(AIS)患者而言,及时的医疗救治至关重要,因为延误可能会对治疗结果产生重大影响。这些延误受到社会文化、教育和临床等多种因素的综合影响。
进行了深入分析,以评估AIS患者寻求医疗救治延误的发生率和中位持续时间。该研究特别调查了社会文化和临床决定因素对这些延误的独立影响,重点关注移民身份、性别差异和教育水平。采用多变量回归分析来确定这些独立影响,同时控制潜在的混杂因素。
在1419例AIS患者中,82.52%(n = 1171)从症状出现到入院的时间延误超过2小时。中位延误时间为12.3小时。与本地人群相比,移民人群的延误时间更长。年龄较小的男性(<45岁)和老年女性更倾向于延迟寻求医疗救治。确定的延误独立危险因素包括男性(比值比[OR]=1.65[95%置信区间:1.14 - 2.48])、自我承认患有糖尿病(OR = 2.50[95%置信区间:1.21 - 5.17])、小血管病变(OR = 2.07[95%置信区间:1.27 - 3.36])和醒后卒中(OR = 7.04[95%置信区间:3.69 - 13.44])。教育背景(高中及以上)、格拉斯哥昏迷评分3 - 8分(OR = 0.52[95%置信区间:0.09 - 0.69])、了解卒中相关知识(OR = 0.26[95%置信区间:0.09 - 0.44])、意识障碍(OR = 0.25[95%置信区间:0.10 - 0.62])和肢体无力(OR = 0.21[95%置信区间:0.21 - 0.49])是及时治疗的保护因素。
移民人群从症状出现到入院的延误时间更长。教育和卒中知识的关键作用凸显了加强健康素养宣传活动和公众意识的必要性,尤其应针对年轻男性和老年女性。