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非典型血管纤维瘤:4例报告

Atypical angiofibromas: a report of four cases.

作者信息

Celik Bilge, Erisen Levent, Saraydaroglu Ozlem, Coskun Hakan

机构信息

University of Uludag School of Medicine, Department of Otolaryngology-Head and Neck Surgery, Bursa, Turkey.

出版信息

Int J Pediatr Otorhinolaryngol. 2005 Mar;69(3):415-21. doi: 10.1016/j.ijporl.2004.10.007. Epub 2004 Dec 28.

Abstract

In this study, our four patients with angiofibroma with various atypical features are presented. Related literature is reviewed and criteria for atypicality are proposed. 14 patients, diagnosed and treated for angiofibroma in the Otorhinolaryngology Department of Faculty of Medicine in Uludag University between January 1992 and December 2003, have been evaluated. The files of the patients were examined and four patients with atypical characteristics have been included in the study. Angiofibromas presenting with at least one of the following criteria such as origin or location other than nasopharynx, presenting complaints other than nasal obstruction or epistaxis, aged younger than seven or older than 25, female sex, atypical histopathology and multifocalitiy were considered as "atypical". Four of 14 angiofibromas (28.5%), which were diagnosed and treated in our clinic, had atypical features. The reasons for atypicality were unusual localization in three patients and uncommon initial symptom in one case. In the atypical localization group, neoplasm was located in tonsil in one case, and in inferior turbinate in two patients. The only patient with atypical initial symptom presented with a bulging in the cheek. The patients, who have different characteristics other than classical angiofibromas, may be called "Atypical Angiofibroma (AAF)", under the scope of the related literature and our experience. These patients should be included in atypical group according to the characteristics such as, localization, symptom, age, sex, histopathology and multifocality.

摘要

本研究报告了4例具有各种非典型特征的血管纤维瘤患者。回顾了相关文献并提出了非典型性标准。对1992年1月至2003年12月期间在乌鲁达大学医学院耳鼻喉科诊断和治疗的14例血管纤维瘤患者进行了评估。检查了患者的病历,4例具有非典型特征的患者被纳入研究。血管纤维瘤若具有以下至少一项标准,如起源或位置不在鼻咽部、除鼻塞或鼻出血外的其他主诉、年龄小于7岁或大于25岁、女性、非典型组织病理学和多灶性,则被视为“非典型”。在我们诊所诊断和治疗的14例血管纤维瘤中,有4例(28.5%)具有非典型特征。非典型性的原因是3例患者肿瘤定位异常,1例患者初始症状不常见。在非典型定位组中,1例肿瘤位于扁桃体,2例位于下鼻甲。唯一具有非典型初始症状的患者表现为脸颊肿胀。根据相关文献和我们的经验,具有不同于经典血管纤维瘤特征的患者可称为“非典型血管纤维瘤(AAF)”。这些患者应根据其定位、症状、年龄、性别、组织病理学和多灶性等特征纳入非典型组。

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