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贾第虫是活化石吗?

Is Giardia a living fossil?

作者信息

Graczyk Thaddeus K

机构信息

Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, 615 North Wolfe Street, Baltimore, MD 21205, USA.

出版信息

Trends Parasitol. 2005 Mar;21(3):104-7. doi: 10.1016/j.pt.2005.01.002.

DOI:10.1016/j.pt.2005.01.002
PMID:15734655
Abstract

Despite enormous efforts, the patterns of the rise of eukaryotic life on Earth are not clearly defined. The ability of eukaryotes to produce energy using oxygen and sugars was a key factor in advancing life on Earth towards complex multicellular organisms. However, this was not the only way to produce energy and survive. Mitochondria probably appeared soon after the oxygen increase in the Earth's atmosphere but many microaerophilic protists require little or no oxygen to survive. New ultrastructural, biochemical and molecular phylogeny data about structures and processes involved in the generation of energy by currently known protists have forced the revision of understanding of the "tree of life".

摘要

尽管付出了巨大努力,但地球上真核生物生命崛起的模式仍未明确界定。真核生物利用氧气和糖类产生能量的能力是推动地球上的生命朝着复杂多细胞生物发展的关键因素。然而,这并非产生能量和生存的唯一方式。线粒体可能在地球大气中氧气增加后不久就出现了,但许多微需氧原生生物生存所需的氧气很少或根本不需要氧气。有关目前已知原生生物能量产生所涉及的结构和过程的新的超微结构、生化和分子系统发育数据,迫使人们对“生命之树”的理解进行修正。

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Is Giardia a living fossil?贾第虫是活化石吗?
Trends Parasitol. 2005 Mar;21(3):104-7. doi: 10.1016/j.pt.2005.01.002.
2
A molecular timescale of eukaryote evolution and the rise of complex multicellular life.真核生物进化的分子时间尺度与复杂多细胞生命的兴起。
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The effect of oxygen on biochemical networks and the evolution of complex life.氧气对生物化学网络及复杂生命演化的影响。
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Life and the evolution of Earth's atmosphere.生命与地球大气的演化
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引用本文的文献

1
Plasmid vectors for proteomic analyses in Giardia: purification of virulence factors and analysis of the proteasome.用于贾第虫蛋白质组学分析的质粒载体:毒力因子的纯化及蛋白酶体分析
Eukaryot Cell. 2012 Jul;11(7):864-73. doi: 10.1128/EC.00092-12. Epub 2012 May 18.
2
Core histone genes of Giardia intestinalis: genomic organization, promoter structure, and expression.肠贾第虫核心组蛋白基因:基因组组织、启动子结构及表达
BMC Mol Biol. 2007 Apr 10;8:26. doi: 10.1186/1471-2199-8-26.
3
Prokaryotic and eukaryotic features observed on the secondary structures of Giardia SSU rRNAs and its phylogenetic implications.
贾第虫小亚基核糖体核糖核酸二级结构中观察到的原核生物和真核生物特征及其系统发育意义。
Parasitol Res. 2007 Apr;100(5):1159-63. doi: 10.1007/s00436-007-0471-5. Epub 2007 Feb 6.
4
The cenH3 histone variant defines centromeres in Giardia intestinalis.着丝粒特异性组蛋白H3变体定义了肠贾第虫中的着丝粒。
Chromosoma. 2007 Apr;116(2):175-84. doi: 10.1007/s00412-006-0091-3. Epub 2006 Dec 20.