Erola Tuomo, Karinen Petri, Heikkinen Esa, Tuominen Juho, Haapaniemi Tarja, Koivukangas John, Myllylä Vilho
Department of Neurosurgery, Oulu University Hospital, P.O. Box 21, FIN-90029 Oys, Finland.
Parkinsonism Relat Disord. 2005 Mar;11(2):89-94. doi: 10.1016/j.parkreldis.2004.08.006.
Parkinson's disease (PD) is a common neurological disorder. Recently, bilateral deep brain stimulation (DBS) of the subthalamic nucleus (STN) has become an option in the treatment of severe PD. We measured the health-related quality of life (HRQoL) of 27 parkinsonian patients, who underwent a bilateral STN-operation. The instruments used for the evaluation of the HRQoL were the Parkinson's Disease Questionnaire (PDQ-39) and the Finnish version of the Nottingham Health Profile (NHP). We found that the quality of life significantly improved when measured with both HRQoL scales. Clinical improvement and improvement in HRQoL were positively correlated.
帕金森病（PD）是一种常见的神经疾病。最近，双侧丘脑底核（STN）深部脑刺激（DBS）已成为重度帕金森病治疗的一种选择。我们对27例接受双侧STN手术的帕金森病患者的健康相关生活质量（HRQoL）进行了测量。用于评估HRQoL的工具是帕金森病问卷（PDQ - 39）和芬兰版的诺丁汉健康量表（NHP）。我们发现，使用这两种HRQoL量表测量时，生活质量均有显著改善。临床改善与HRQoL的改善呈正相关。
