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“非体外循环”心脏手术的安全性与有效性。

The safety and efficacy of "bloodless" cardiac surgery.

作者信息

Shander Aryeh, Moskowitz David, Rijhwani Tanuja S

机构信息

Critical Care Medicine, Pain Management and Hyperbaric Medicine, Englewood Hospital and Medical Center, Englewood, NJ 07361, USA.

出版信息

Semin Cardiothorac Vasc Anesth. 2005 Mar;9(1):53-63. doi: 10.1177/108925320500900106.

Abstract

Nearly 20% of blood transfusions in the United States are associated with cardiac surgery. Despite the many blood conservation techniques that are available, safe, and efficacious for patients undergoing cardiac surgery, many of these operations continue to be associated with significant amounts of blood transfusion. Although surgical bleeding after cardiopulmonary bypass is a common problem as reflected by the substantial use of blood products, it is the individual physician and institutional behavior that have been identified as reasons for transfusion and not necessarily patient comorbidity or blood loss. Transfusion rates in cardiac surgery remain high despite major advances in perioperative blood conservation, with large variations among individual centers. The adoption of available blood conservation techniques, either alone or in combination in patients undergoing cardiac surgery, could result in an estimated 75% reduction of unnecessary transfusions. The success of previously reported blood conservations programs in cardiac surgery should call for a reevaluation of allogeneic transfusion practices in patients undergoing cardiac surgery. By applying the numerous reported blood conservation strategies for the management of patients presenting for cardiac surgery, we can preserve our dwindling blood resources and help alleviate some of the direct costs of blood as well as the indirect costs of treating noninfectious and infectious complications of transfusion.

摘要

在美国,近20%的输血与心脏手术有关。尽管有许多血液保护技术可供心脏手术患者使用,且安全有效,但许多此类手术仍与大量输血有关。尽管体外循环后的手术出血是一个常见问题,这从大量使用血液制品中可见一斑,但已确定个人医生和机构行为是输血的原因,而不一定是患者的合并症或失血。尽管围手术期血液保护取得了重大进展,但心脏手术的输血率仍然很高,各中心之间存在很大差异。在接受心脏手术的患者中单独或联合采用现有的血液保护技术,估计可减少75%的不必要输血。先前报道的心脏手术血液保护项目的成功应促使对心脏手术患者的异体输血做法进行重新评估。通过应用众多已报道的用于管理心脏手术患者的血液保护策略,我们可以保护日益减少的血液资源,并有助于减轻一些血液的直接成本以及治疗输血的非感染性和感染性并发症的间接成本。

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