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自体输血与非自体输血对冠状动脉搭桥术后优势、劣势、拔管时间及出血影响的比较

Comparison of the effects of autologous and non-autologous blood transfusions on the advantages, disadvantages, extubation time and bleeding after coronary bypass.

作者信息

Yıldız Ziya, Kayğın Mehmet Ali

机构信息

Turkish Society of Cardiovascular Surgery, Turkish Society of Vascular and Endovascular Surgery, Palandöken, 25040, Erzurum, Turkey.

出版信息

Heliyon. 2023 Jun 15;9(6):e17371. doi: 10.1016/j.heliyon.2023.e17371. eCollection 2023 Jun.

DOI:10.1016/j.heliyon.2023.e17371
PMID:37383208
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10293705/
Abstract

PURPOSE

Blood transfusion; is considered an organ transplant. In coronary bypass surgery, large volumes of homologous blood transfusion may be required due to excessive bleeding. The large number of use of homologous blood transfusion in open heart surgery and the awareness of its various harmful effects have prompted researchers to conduct research on the use of autologous blood. With autologous transfusion, blood diseases, incompatibility, immunosuppression and organ damage can be prevented and the patient can be extubated earlier in the postoperative period.

METHODS

Between January 2020 and January 2016, a total of 176 patients, 56 in the treatment group (with autologous blood transfusion) and 120 in the control group, whose information could be reached from hospital records were investigated retrospectively.

RESULTS

No statistical difference was found between the mean intubation SO2 and PO2 values of the groups. On the contrary, considering the mean intubation times in the intensive care unit of both groups, the patients who underwent autologous blood transfusion were extubated at a statistically significant earlier time.

CONCLUSION

Autologous blood transfusion is a safe method in selected patients as well. Thanks to this method, patients are protected from complications associated with homologous blood transfusion. It is believed that performing autologous blood transfusion in selected patients undergoing open-heart surgery can decrease the number of postoperative transfusions, frequency of transfusion-related complications (especially in the lungs), and mean intubation times.

摘要

目的

输血被视为一种器官移植。在冠状动脉搭桥手术中,由于出血过多可能需要大量输注同源血。心脏直视手术中大量使用同源血以及对其各种有害影响的认识促使研究人员对自体血的使用进行研究。通过自体输血,可以预防血液疾病、不相容性、免疫抑制和器官损伤,并且患者在术后可以更早拔管。

方法

回顾性调查2020年1月至2016年1月期间,从医院记录中获取信息的总共176例患者,治疗组56例(采用自体输血),对照组120例。

结果

两组的平均插管时SO2和PO2值之间未发现统计学差异。相反,考虑两组在重症监护病房的平均插管时间,接受自体输血的患者拔管时间在统计学上显著更早。

结论

自体输血对选定患者也是一种安全的方法。通过这种方法,患者可免受与同源输血相关的并发症影响。据信,在选定的心脏直视手术患者中进行自体输血可以减少术后输血次数、输血相关并发症(尤其是肺部)的发生率以及平均插管时间。

相似文献

1
Comparison of the effects of autologous and non-autologous blood transfusions on the advantages, disadvantages, extubation time and bleeding after coronary bypass.自体输血与非自体输血对冠状动脉搭桥术后优势、劣势、拔管时间及出血影响的比较
Heliyon. 2023 Jun 15;9(6):e17371. doi: 10.1016/j.heliyon.2023.e17371. eCollection 2023 Jun.
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[Preoperative autologous blood donation with cardiac surgery].[心脏手术的术前自体血捐献]
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Autologous blood donations prior to elective cardiac surgery. Safety and effect on subsequent blood use.择期心脏手术前的自体血捐献。安全性及对后续用血的影响。
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本文引用的文献

1
Seroprevalence of transfusion-transmissible infections among blood donors at National Blood Transfusion Service, Eritrea: a seven-year retrospective study.厄立特里亚国家血液服务中心献血者中输血传播感染的血清流行率:一项为期七年的回顾性研究。
BMC Infect Dis. 2018 Jun 7;18(1):264. doi: 10.1186/s12879-018-3174-x.
2
Patient blood management: is it worth to be employed?患者血液管理:是否值得采用?
Curr Opin Anaesthesiol. 2016 Apr;29(2):186-91. doi: 10.1097/ACO.0000000000000298.
3
Greater Volume of Acute Normovolemic Hemodilution May Aid in Reducing Blood Transfusions After Cardiac Surgery.更大容量的急性等容血液稀释可能有助于减少心脏手术后的输血。
Ann Thorac Surg. 2015 Nov;100(5):1581-7; discussion 1587. doi: 10.1016/j.athoracsur.2015.04.135. Epub 2015 Jul 21.
4
Transfusion reactions: newer concepts on the pathophysiology, incidence, treatment, and prevention of transfusion-related acute lung injury.输血反应:关于输血相关急性肺损伤的病理生理学、发生率、治疗和预防的新概念。
Crit Care Clin. 2012 Jul;28(3):363-72, v. doi: 10.1016/j.ccc.2012.04.001.
5
Red cell transfusion is associated with an increased risk for postoperative atrial fibrillation.红细胞输血与术后房颤风险增加有关。
Ann Thorac Surg. 2006 Nov;82(5):1747-56. doi: 10.1016/j.athoracsur.2006.05.045.
6
Morbidity and mortality risk associated with red blood cell and blood-component transfusion in isolated coronary artery bypass grafting.单纯冠状动脉旁路移植术中红细胞及血液成分输血相关的发病和死亡风险
Crit Care Med. 2006 Jun;34(6):1608-16. doi: 10.1097/01.CCM.0000217920.48559.D8.
7
The safety and efficacy of "bloodless" cardiac surgery.“非体外循环”心脏手术的安全性与有效性。
Semin Cardiothorac Vasc Anesth. 2005 Mar;9(1):53-63. doi: 10.1177/108925320500900106.
8
Possible mechanisms underlying development of transfusion-related acute lung injury: roles of anti-major histocompatibility complex class II DR antibody.输血相关急性肺损伤发生的潜在机制:抗主要组织相容性复合体II类DR抗体的作用
Transfus Med. 2003 Jun;13(3):141-7. doi: 10.1046/j.1365-3148.2003.00434.x.
9
Plasma and lipids from stored platelets cause acute lung injury in an animal model.储存血小板中的血浆和脂质在动物模型中可导致急性肺损伤。
Transfusion. 2003 May;43(5):633-40. doi: 10.1046/j.1537-2995.2003.00385.x.
10
Current prevalence and incidence of infectious disease markers and estimated window-period risk in the American Red Cross blood donor population.美国红十字会献血人群中传染病标志物的当前流行率和发病率以及估计的窗口期风险。
Transfusion. 2002 Aug;42(8):975-9. doi: 10.1046/j.1537-2995.2002.00174.x.