Chan G C
Peringgit Community Polyclinic, Jalan Pantai Peringgit, 75400 Melaka, Malaysia.
Singapore Med J. 2005 Mar;46(3):127-31.
A study was conducted at primary healthcare level in the Melaka Tengah district of Malaysia to determine whether hypertension in patients with type 2 diabetes mellitus were managed according to guidelines.
A cross-sectional study involving 517 patients with diabetes mellitus from August to October 2003 was performed.
All the subjects had type 2 diabetes mellitus. 350 (67.7 percent) patients had hypertension and about 25.7 percent of them were associated with microalbuminuria. The Malay ethnic group form the majority (54.6 percent), followed by Chinese (37.7 percent) and Indian (7.4 percent). Only 11 (3.1 percent) patients with type 2 diabetes mellitus and hypertension achieved the target blood pressure of less than 130/80 mmHg. For those who had not achieved the target goal, 39.5 percent of them were not on any antihypertensive drugs. 38.6 percent were on monotherapy and only 21.8 percent were on two or more antihypertensive drugs. Metoprolol was the most commonly used antihypertensive drug (22.4 percent), followed by Nifedipine (16.2 percent) and Prazosin (13.5 percent). Only 18.3 percent of patients with type 2 diabetes mellitus and hypertension were prescribed with angiotensin converting enzyme (ACE) inhibitors and 0.3 percent with angiotensin receptor blockers. For patients with type 2 diabetes mellitus, hypertension and microalbuminuria, only 14.1 percent of them were prescribed with ACE inhibitors.
A significant proportion of patients with type 2 diabetes mellitus had associated hypertension but they were not managed optimally according to guidelines. More intensive management of hypertension among patients with diabetes is essential to reduce the morbidity and mortality at primary healthcare level.
在马来西亚马六甲中区的基层医疗保健机构开展了一项研究,以确定2型糖尿病患者的高血压是否按照指南进行管理。
于2003年8月至10月进行了一项横断面研究,纳入517例糖尿病患者。
所有受试者均为2型糖尿病患者。350例(67.7%)患者患有高血压,其中约25.7%伴有微量白蛋白尿。马来族占多数(54.6%),其次是华族(37.7%)和印族(7.4%)。仅有11例(3.1%)2型糖尿病合并高血压患者达到了血压目标值低于130/80 mmHg。对于未达目标值的患者,39.5%未服用任何降压药物。38.6%接受单药治疗,仅21.8%服用两种或更多种降压药物。美托洛尔是最常用的降压药物(22.4%),其次是硝苯地平(16.2%)和哌唑嗪(13.5%)。仅有18.3%的2型糖尿病合并高血压患者使用了血管紧张素转换酶(ACE)抑制剂,0.3%使用了血管紧张素受体阻滞剂。对于2型糖尿病合并高血压及微量白蛋白尿的患者,仅14.1%使用了ACE抑制剂。
相当一部分2型糖尿病患者合并高血压,但未按照指南进行优化管理。加强糖尿病患者的高血压管理对于降低基层医疗保健机构的发病率和死亡率至关重要。