Lee S H, Ewert D P, Frederick P D, Mascola L
Division of Field Epidemiology, Centers for Disease Control, Los Angeles, CA.
JAMA. 1992 May 20;267(19):2616-20.
To assess previous missed opportunities for rubella screening and vaccination of women delivering infants with congenital rubella syndrome and to discuss prevention strategies.
Descriptive analysis of data collected through interviews and review of medical records.
Twenty-one women who delivered infants with congenital rubella syndrome in four Southern California counties from January 1, 1990, through January 8, 1991.
Twelve (57%) of the women had a total of 22 known missed opportunities for rubella screening or vaccination. Of the 22 missed opportunities, three (14%) were missed screenings at the time of marriage, two (9%) were missed screenings during previous pregnancies, five (23%) were missed screenings during induced abortions, and 12 (55%) were missed opportunities for vaccination postpartum or after induced abortions. Nine (43%) of the women had no known missed opportunities for rubella screening or vaccination. Of 12 women educated in California, only four (33%) were subject to the 1982 California school rubella immunization requirement.
Congenital rubella syndrome could have been prevented in more than half of the infants born to these women if missed opportunities for rubella testing and/or vaccination had not occurred. Because premarital rubella testing and school immunization requirements do not ensure that all women of childbearing age are immune to rubella, physicians and hospitals should establish procedures for postpartum rubella vaccination of susceptible women. Family planning and abortion clinics should implement routine rubella testing and follow-up vaccination of susceptible women.
评估既往在对分娩先天性风疹综合征患儿的妇女进行风疹筛查和疫苗接种方面错过的机会,并探讨预防策略。
通过访谈和病历审查收集的数据进行描述性分析。
1990年1月1日至1991年1月8日在南加州四个县分娩先天性风疹综合征患儿的21名妇女。
12名(57%)妇女共有22次已知的风疹筛查或疫苗接种错过机会。在这22次错过的机会中,3次(14%)是结婚时错过的筛查,2次(9%)是既往妊娠期间错过的筛查,5次(23%)是人工流产时错过的筛查,12次(55%)是产后或人工流产后错过的疫苗接种机会。9名(43%)妇女没有已知的风疹筛查或疫苗接种错过机会。在加利福尼亚接受教育的12名妇女中,只有4名(33%)符合1982年加利福尼亚州学校风疹免疫要求。
如果没有出现风疹检测和/或疫苗接种错过机会的情况,这些妇女所生婴儿中超过一半的先天性风疹综合征本可得到预防。由于婚前风疹检测和学校免疫要求并不能确保所有育龄妇女对风疹免疫,医生和医院应制定对易感妇女进行产后风疹疫苗接种的程序。计划生育和堕胎诊所应实施对易感妇女的常规风疹检测和后续疫苗接种。