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果蝇的研究资源:不断扩展的领域

Research resources for Drosophila: the expanding universe.

作者信息

Matthews Kathleen A, Kaufman Thomas C, Gelbart William M

机构信息

Department of Biology, Indiana University, Bloomington, Indiana 47405-3700, USA.

出版信息

Nat Rev Genet. 2005 Mar;6(3):179-93. doi: 10.1038/nrg1554.

Abstract

Drosophila melanogaster has been the subject of research into central questions about biological mechanisms for almost a century. The experimental tools and resources that are available or under development for D. melanogaster and its related species, particularly those for genomic analysis, are truly outstanding. Here we review three types of resource that have been developed for D. melanogaster research: databases and other sources of information, biological materials and experimental services. These resources are there to be exploited and we hope that this guide will encourage new uses for D. melanogaster information, materials and services, both by those new to flies and by experienced D. melanogaster researchers.

摘要

近一个世纪以来,黑腹果蝇一直是生物学机制核心问题研究的对象。现有的或正在为黑腹果蝇及其相关物种开发的实验工具和资源,尤其是那些用于基因组分析的工具和资源,堪称卓越。在这里,我们回顾为黑腹果蝇研究开发的三类资源:数据库和其他信息来源、生物材料和实验服务。这些资源有待开发利用,我们希望本指南将鼓励初涉果蝇研究的人员以及经验丰富的黑腹果蝇研究人员对黑腹果蝇的信息、材料和服务进行新的应用。

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