Timon C I, Gullane P J, Brown D, Van Nostrand A W
Department of Otolaryngology-Head and Neck Surgery, Toronto General Hospital.
Laryngoscope. 1992 May;102(5):515-20. doi: 10.1288/00005537-199205000-00008.
The incidence of hyoid bone involvement by neoplasia is undetermined, despite its importance in hyoid-preserving surgery. Eleven (1.46%) of 755 whole-organ laryngeal specimens examined demonstrated hyoid bone infiltration. These included 6 cases originating from the larynx, 3 from the vallecula, and 1 case each from the pyriform fossa and tongue base. Clinically, vallecular involvement was helpful in determining hyoid invasion; however, computed tomography (CT) was disappointing. The greater cornu was the sole site of invasion in six cases. Ten of 11 cases were secondary to direct tumor spread. All carcinomas were advanced, with variable differentiation. Vascular and neural invasion was a prominent feature. Hyoid bone invasion is rare, and associated with a poor prognosis. Hyoid bone preservation is feasible in a majority of patients.
尽管舌骨在保留舌骨的手术中具有重要性，但其受肿瘤累及的发生率尚不确定。在检查的755个全喉标本中，有11个（1.46%）显示有舌骨浸润。其中包括6例起源于喉部，3例起源于会厌谷，梨状窝和舌根各1例。临床上，会厌谷受累有助于确定舌骨侵犯；然而，计算机断层扫描（CT）的表现却不尽人意。6例中，舌骨大角是唯一的侵犯部位。11例中有10例是肿瘤直接蔓延所致。所有癌均为进展期，分化程度不一。血管和神经侵犯是一个突出特征。舌骨侵犯罕见，且预后不良。大多数患者可行舌骨保留术。
