Al Snih Soham, Markides Kyriakos S, Ottenbacher Kenneth J, Raji Mukaila A
Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX 77555-0460, USA.
Aging Clin Exp Res. 2004 Dec;16(6):481-6. doi: 10.1007/BF03327406.
Little is known about muscle strength as a predictor of disability among older Mexican Americans. The aim of this study was to examine the association between hand grip strength and 7-year incidence of ADL disability in older Mexican American men and women.
A 7-year prospective cohort study of 2493 non-institutionalized Mexican American men and women aged 65 or older residing in five south-western states. Maximal hand grip strength test, body mass index, cognitive function, activities of daily living, self-reports of medical conditions (arthritis, diabetes, heart attack, stroke, cancer, hip fracture), and depressive symptoms were obtained.
In a Cox proportional regression analysis, there was a linear relationship between hand grip strength at baseline and risk of incident ADL disability over a 7-year follow-up. Among non-disabled men at baseline, the hazard ratio of any new ADL limitation was 1.90 (95% CI 1.14-3.17) for those in the lowest quartile, when compared with men in the highest hand grip strength quartile, after controlling for age, marital status, medical conditions, high depressive symptoms, MMSE score, and BMI at baseline. Among non-disabled women at baseline, the hazard ratio of any new ADL limitation was 2.28 (95% CI 1.59-3.27) for those in the lowest quartile, when compared with women in the highest hand grip strength quartile.
Hand grip strength is an independent predictor of ADL disability among older Mexican American men and women. The hand grip strength test is an easy, reliable, valid, inexpensive method of screening to identify older adults at risk of disability.
关于肌肉力量作为老年墨西哥裔美国人残疾预测指标的研究较少。本研究旨在探讨握力与老年墨西哥裔美国男性和女性日常生活活动（ADL）残疾7年发病率之间的关联。
对居住在五个西南部州的2493名65岁及以上非机构化墨西哥裔美国男性和女性进行了为期7年的前瞻性队列研究。获取了最大握力测试、体重指数、认知功能、日常生活活动、医疗状况（关节炎、糖尿病、心脏病发作、中风、癌症、髋部骨折）的自我报告以及抑郁症状。
在Cox比例回归分析中，基线时的握力与7年随访期间发生ADL残疾的风险之间存在线性关系。在基线时无残疾的男性中，在控制了年龄、婚姻状况、医疗状况、高抑郁症状、简易精神状态检查表（MMSE）评分和基线体重指数后，与握力最强四分位数组的男性相比，握力最低四分位数组的男性出现任何新的ADL限制的风险比为1.90（95%置信区间1.14 - 3.17）。在基线时无残疾的女性中，与握力最强四分位数组的女性相比，握力最低四分位数组的女性出现任何新的ADL限制的风险比为2.28（95%置信区间1.59 - 3.27）。
握力是老年墨西哥裔美国男性和女性ADL残疾的独立预测指标。握力测试是一种简单、可靠、有效且廉价的筛查方法，可用于识别有残疾风险的老年人。
