Ble Alesandro, Volpato Stefano, Zuliani Giovanni, Guralnik Jack M, Bandinelli Stefania, Lauretani Fulvio, Bartali Benedetta, Maraldi Cinzia, Fellin Renato, Ferrucci Luigi
Longitudinal Studies Section, Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland.
J Am Geriatr Soc. 2005 Mar;53(3):410-5. doi: 10.1111/j.1532-5415.2005.53157.x.
To study the association between performance on psychological tests of executive function and performance on lower extremity tasks with different attentional demands in a large sample of nondemented, older adults.
Cross-sectional study.
Community-based.
Nine hundred twenty-six persons aged 65 and older, without dementia, stroke, parkinsonism, visual impairment, or current treatment with neuroleptics, enrolled in a large epidemiological study.
Trail Making Test (TMT) parts A and B and two performance-based measures of lower extremity function that require different executive/attentional-demanding skills: walking speed on a 4-m course at usual pace and walking speed on a 7-m obstacle course at fast pace. A difference score (Delta TMT), obtained by subtracting time to perform part A from time to perform part B of the TMT, was used as an indicator of executive function. Based on Delta TMT, subjects were divided into poor performance, intermediate performance, and good performance.
After adjustment, no association between Delta TMT and 4-m course usual-pace walking speed was found. Participants with poor Delta TMT and with intermediate Delta TMT performance were more likely to be in the lowest tertile for 7-m obstacle course walking speed.
In nondemented older persons, executive function is independently associated with tasks of lower extremity function that require high attentional demand.
在大量无痴呆的老年人样本中，研究执行功能心理测试表现与不同注意力需求的下肢任务表现之间的关联。
横断面研究。
基于社区。
926名65岁及以上的老年人，无痴呆、中风、帕金森病、视力障碍或目前正在接受抗精神病药物治疗，参加了一项大型流行病学研究。
连线测验（TMT）A部分和B部分，以及两项基于表现的下肢功能测量指标，这两项指标需要不同的执行/注意力需求技能：4米路线上的正常步速行走速度和7米障碍路线上的快速步速行走速度。通过用TMT B部分的完成时间减去A部分的完成时间得到的差异分数（Delta TMT），被用作执行功能的指标。根据Delta TMT，将受试者分为表现差、表现中等和表现良好三组。
调整后，未发现Delta TMT与4米路线正常步速行走速度之间存在关联。Delta TMT表现差和表现中等的参与者在7米障碍路线行走速度方面更有可能处于最低三分位数。
在无痴呆的老年人中，执行功能与需要高注意力需求的下肢功能任务独立相关。
