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[冠状动脉血运重建:临床特征与适应症]

[Coronary revascularization: clinical features and indications].

作者信息

Alonso Martín Joaquín J, Curcio Ruigómez Alejandro, Cristóbal Varela Carmen, Tarín Vicente María Nieves, Serrano Antolín José María, Talavera Calle Pedro, Graupner Abad Catherine

机构信息

Servicio de Cardiología Hospital de Fuenlabrada, Madrid, España.

出版信息

Rev Esp Cardiol. 2005 Feb;58(2):198-216.

Abstract

Coronary artery revascularization is an established therapeutic intervention and is therefore included in all treatment guidelines for patients with coronary artery disease. Although the procedure has been available for more than 40 years, constant technical progress in surgical and percutaneous revascularization continues to bring the benefits of revascularization therapy to new groups of patients. Therefore the indications and limitations of this approach need to be reviewed and updated periodically. The aim of revascularization therapy is to improve the prognosis or symptoms and quality of life in patients with ischemic heart disease. The revascularization process comprises two aspects: 1) indication and selection of the revascularization procedure, and 2) performance of the procedure. Involvement of the clinical cardiologist in the first step is fundamental. Basing their decisions on clinical, functional and anatomical features, these professionals detect and select patients who would benefit, and also help to select the revascularization technique. In this Update article on revascularization we review, for stable ischemic heart disease and non-ST segment elevation acute coronary syndromes, the following: 1) the most relevant aspects to consider when evaluating the need for and the type of revascularization (age, sex, diabetes, renal function, electrocardiographic changes, ventricular function and quantification of functional relevance of coronary artery disease and viability of the acinetic areas); 2) indications for surgical or percutaneous intervention, and the choice of therapeutic strategy according to the latest clinical evidence and guidelines of scientific societies, and 3) currently available data on the controversy regarding choice of the revascularization procedure in patients with multivessel disease.

摘要

冠状动脉血运重建是一种既定的治疗干预措施,因此被纳入所有冠心病患者的治疗指南中。尽管该手术已应用超过40年,但外科和经皮血运重建技术的不断进步持续为新的患者群体带来血运重建治疗的益处。因此,需要定期回顾和更新这种治疗方法的适应证和局限性。血运重建治疗的目的是改善缺血性心脏病患者的预后、症状及生活质量。血运重建过程包括两个方面:1)血运重建手术的适应证和选择;2)手术的实施。临床心脏病专家参与第一步至关重要。这些专业人员根据临床、功能和解剖学特征做出决策,识别和选择可能受益的患者,并协助选择血运重建技术。在这篇关于血运重建的更新文章中,我们针对稳定型缺血性心脏病和非ST段抬高型急性冠状动脉综合征,回顾以下内容:1)评估血运重建需求和类型时最相关的方面(年龄、性别、糖尿病、肾功能、心电图变化、心室功能以及冠状动脉疾病功能相关性的量化和运动减弱区域的存活情况);2)外科或经皮介入的适应证,以及根据科学学会的最新临床证据和指南选择治疗策略;3)目前关于多支血管病变患者血运重建手术选择争议的现有数据。

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