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鼻瓣手术可改善疾病特异性生活质量。

Nasal valve surgery improves disease-specific quality of life.

作者信息

Rhee John S, Poetker David M, Smith Timothy L, Bustillo Andres, Burzynski Mary, Davis Richard E

机构信息

Department of Otolaryngology and Communication Sciences, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.

出版信息

Laryngoscope. 2005 Mar;115(3):437-40. doi: 10.1097/01.mlg.0000157831.46250.ad.

DOI:10.1097/01.mlg.0000157831.46250.ad
PMID:15744153
Abstract

OBJECTIVES/HYPOTHESIS: Disease-specific quality-of-life (QOL) assessment of patients with nasal valve compromise and symptomatic nasal obstruction has not been studied previously. The objectives of the study were to determine whether surgical treatment of the nasal valve improves disease-specific QOL and to identify clinical or demographic variables predictive of patients' baseline QOL or change in QOL.

STUDY DESIGN

Prospective, multi-institutional outcomes study of 20 patients with nasal obstruction and a surgically treatable diagnosis of nasal valve compromise.

METHODS

Disease-specific QOL assessment was performed using the Nasal Obstruction Symptom Evaluation (NOSE) scale preoperatively (n = 20) and at 3 (n = 14) and 6 months (n = 20) after surgery. Clinical and demographic data were collected, along with physician-reported assessments of degree of nasal obstruction.

RESULTS

Mean NOSE scores significantly improved from baseline to 3 months after surgery (68.9 vs. 20.7 [P < .0001]), from baseline to 6 months after surgery (68.9 vs. 15.8 [P < .0001]), and from 3 to 6 months after surgery (20.7 vs. 15.8 [P = .0077]). Physician assessment of degree of nasal obstruction using a visual analogue scale was significantly correlated with baseline NOSE scores (P = .013) and change in NOSE scores at 6 months (P = .0015). No other clinical or demographic factors were found to be predictive.

CONCLUSION

In patients with symptomatic nasal obstruction and nasal valve compromise, surgical repair of the nasal valve improves disease-specific QOL. Physician rating of degree of nasal obstruction was found to be significantly correlated with patient-reported QOL.

摘要

目的/假设:此前尚未对鼻瓣膜受损且有症状性鼻阻塞患者进行疾病特异性生活质量(QOL)评估。本研究的目的是确定鼻瓣膜的手术治疗是否能改善疾病特异性生活质量,并识别预测患者基线生活质量或生活质量变化的临床或人口统计学变量。

研究设计

对20例有鼻阻塞且经手术可治疗诊断为鼻瓣膜受损的患者进行前瞻性、多机构结局研究。

方法

术前(n = 20)以及术后3个月(n = 14)和6个月(n = 20)使用鼻阻塞症状评估(NOSE)量表进行疾病特异性生活质量评估。收集临床和人口统计学数据,以及医生报告的鼻阻塞程度评估。

结果

从基线到术后3个月,平均NOSE评分显著改善(68.9对20.7 [P < .0001]),从基线到术后6个月(68.9对15.8 [P < .0001]),以及从术后3个月到6个月(20.7对15.8 [P = .0077])。医生使用视觉模拟量表对鼻阻塞程度的评估与基线NOSE评分(P = .013)和6个月时NOSE评分的变化(P = .0015)显著相关。未发现其他临床或人口统计学因素具有预测性。

结论

在有症状性鼻阻塞和鼻瓣膜受损的患者中,鼻瓣膜的手术修复可改善疾病特异性生活质量。发现医生对鼻阻塞程度的评级与患者报告的生活质量显著相关。

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