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澳大利亚儿童季节性呼吸道疾病的成本:患者及家庭成本的主导地位及其对疫苗使用的影响。

The cost of seasonal respiratory illnesses in Australian children: the dominance of patient and family costs and implications for vaccine use.

作者信息

Lambert Stephen, O'Grady Kerry-Ann, Gabriel Susan, Carter Robert, Nolan Terry

机构信息

Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, Victoria.

出版信息

Commun Dis Intell Q Rep. 2004;28(4):510-6. doi: 10.33321/cdi.2004.28.59.

DOI:10.33321/cdi.2004.28.59
PMID:15745401
Abstract

Respiratory viral infections are one of the next group of diseases likely to be targeted for prevention in childhood by the use of vaccines. To begin collecting necessary epidemiology and cost information about the illnesses caused by these viruses, we conducted a prospective cohort study in 118 Melbourne children between 12 and 71 months of age during winter and spring 2001. We were interested in calculating an average cost per episode of community-managed acute respiratory disease, in identifying the key cost drivers of such illness, and to identify the proportion of costs borne by the patient and family. There were 202 community-managed influenza-like illnesses identified between July and December 2001, generating 89 general practitioner visits, and 42 antibiotic prescriptions. The average cost of community-managed episodes (without hospitalisation) was dollar 241 (95% CI dollar 191 to dollar 291), with the key cost drivers being carer time away from usual activities caring for the ill child (70% of costs), use of non-prescription medications (5.4%), and general practice visits (5.0%). The patient and family met 87 per cent of total costs. The lowest average cost occurred in households from the highest income bracket. Acute respiratory illness managed in the community is common, with the responsibility for meeting the cost of episodes predominantly borne by the patient and family in the form of lost productivity. These findings have implications for preventive strategies in children, such as the individual use of, or implementation of public programs using, currently available vaccines against influenza and vaccines under development against other viral respiratory pathogens.

摘要

呼吸道病毒感染是下一类可能通过疫苗预防的儿童疾病。为了开始收集有关这些病毒所致疾病的必要流行病学和成本信息,我们于2001年冬春季节对118名年龄在12至71个月的墨尔本儿童进行了一项前瞻性队列研究。我们感兴趣的是计算社区管理的急性呼吸道疾病每次发作的平均成本,确定此类疾病的主要成本驱动因素,并确定患者和家庭承担的成本比例。2001年7月至12月期间共确定了202例社区管理的流感样疾病,导致89次全科医生就诊和42次抗生素处方。社区管理的发作(不住院)平均成本为241澳元(95%可信区间为191澳元至291澳元),主要成本驱动因素是照顾患病儿童的护理人员因日常活动而损失的时间(占成本的70%)、非处方药的使用(5.4%)和全科医生就诊(5.0%)。患者和家庭承担了总成本的87%。平均成本最低的是最高收入阶层的家庭。社区管理的急性呼吸道疾病很常见,发作成本主要由患者和家庭以生产力损失的形式承担。这些发现对儿童预防策略有影响,例如个人使用或实施公共项目使用现有的流感疫苗以及正在研发的针对其他病毒性呼吸道病原体的疫苗。

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