Ortega del Alamo P, Rivera Rodríguez T, Sanz Fernández R
Servicio de Otorrinolaringología, Hospital General de Móstoles, Móstoles, Madrid.
Acta Otorrinolaringol Esp. 2005 Jan;56(1):1-5. doi: 10.1016/s0001-6519(05)78561-7.
Otitis media with effusion (OME) is one of the most frequent diseases and the main cause of hearing loss in childhood. The medical treatment for OME includes antibiotics, antihistamine-decongestant combinations, steroids and Eustachian-tube autoinflation as the Valsalva manoeuvre.
A total of 62 children aged 2 to 8 years with a diagnosis of OME were enrolled in a prospective study to assess the resolution of OME. Patients were given antibiotics treatment with or without associated AM3.
After 2 months of treatment, the rate of complete resolution of OME was greater in AM3 treated group than in the non-AM3 treated group (57.6% vs 27.6%) with a statistically significant difference (p<0.017).
These results show that AM3 treatment has a beneficial effect on OME resolution when it is associated to antibiotic treatment.
分泌性中耳炎（OME）是儿童期最常见的疾病之一，也是听力损失的主要原因。OME的药物治疗包括抗生素、抗组胺药 - 减充血剂组合、类固醇以及咽鼓管自动充气法（如瓦尔萨尔瓦动作）。
共有62名年龄在2至8岁、诊断为OME的儿童纳入一项前瞻性研究，以评估OME的缓解情况。患者接受了使用或不使用联合AM3的抗生素治疗。
治疗2个月后，接受AM3治疗的组中OME完全缓解率高于未接受AM3治疗的组（57.6%对27.6%），差异有统计学意义（p<0.017）。
这些结果表明，AM3治疗与抗生素治疗联合使用时，对OME的缓解有有益作用。
