Scheinfeld Noah
Department of Dermatology, St Luke's Roosevelt Hospital, New York, USA.
Dermatol Online J. 2005 Mar 1;11(1):9.
A side effect of the injection of botulinum toxin into the upper third of the face is ptosis or lid droop. A therapy recommended to treat ptosis resulting from administration of botulinum toxins A and B is Iopidine (apraclonidine 0.5 %) eye drops. Apraclonidine is an alpha2-adrenergic agonist, which causes Muller muscles to contract quickly elevating the upper eyelid 1-3 mm. Little published data discusses the use of apraclonidine to treat such ptosis. This communication discusses the extant literature on this usage. Research needs to be done to establish the utility and dosing of apraclonidine for botulinum toxin-induced ptosis.
将肉毒杆菌毒素注射到面部上三分之一部位的一个副作用是上睑下垂或眼睑下垂。推荐用于治疗由A型和B型肉毒杆菌毒素给药导致的上睑下垂的一种疗法是使用艾氟龙（0.5%阿可乐定）眼药水。阿可乐定是一种α2肾上腺素能激动剂，它可使米勒肌快速收缩，使上眼睑抬高1 - 3毫米。很少有已发表的数据讨论使用阿可乐定治疗此类上睑下垂。本交流讨论了关于这种用法的现有文献。需要开展研究以确定阿可乐定用于治疗肉毒杆菌毒素引起的上睑下垂的效用和剂量。
