Nguyen Nathalie Q
Ronald O. Perelman Department of Dermatology, New York University, USA.
Dermatol Online J. 2004 Nov 30;10(3):1.
A 45-year-old man presented with lesions clinically and histologically consistent with telangiectasis macularis eruptiva perstans (TMEP). TMEP is a rare form of mastocytosis, which is localized to the skin, although systemic involvement has been reported. A mutation in the c-kit proto-oncogene is thought to be involved in mast cell hyperplasia in some patients with mastocytosis. Treatment depends on the presence of systemic involvement or clinical symptoms. In case reports, therapeutic benefit has been reported in TMEP with the use of the 585-flashlamp pumped dye lasers and of electron beam radiation.
一名45岁男性患者出现的病变在临床和组织学上与持久性斑疹性毛细血管扩张症（TMEP）相符。TMEP是肥大细胞增多症的一种罕见形式，局限于皮肤，不过也有全身受累的报道。c-kit原癌基因的突变被认为与一些肥大细胞增多症患者的肥大细胞增生有关。治疗取决于是否存在全身受累或临床症状。在病例报告中，使用585脉冲染料激光和电子束辐射治疗TMEP已报道有治疗效果。
