Suppr超能文献

类脂质渐进性坏死

Necrobiosis lipoidica.

作者信息

Wee Sue Ann, Possick Paul

机构信息

Ronald O. Perelman Department of Dermatology, New York University, USA.

出版信息

Dermatol Online J. 2004 Nov 30;10(3):18.

Abstract

A 68-year-old woman presented with a 3-year history of asymptomatic, yellow-brown plaques on the lower extremities with trauma-related superficial ulcers. A biopsy specimen was consistent with necrobiosis lipoidica. Necrobiosis lipoidica is a chronic granulomatous dermatitis that is associated with diabetes mellitus; however, its pathogenesis remains unclear. Topical glucocorticoids are first-line therapy; however, no treatment has proven efficacy in double-blind, placebo-controlled studies.

摘要

一名68岁女性,下肢出现无症状的黄棕色斑块并伴有与创伤相关的浅表溃疡,病史3年。活检标本符合类脂质渐进性坏死。类脂质渐进性坏死是一种与糖尿病相关的慢性肉芽肿性皮炎;然而,其发病机制仍不清楚。外用糖皮质激素是一线治疗方法;然而,在双盲、安慰剂对照研究中,尚无治疗被证明有效。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验