Lange C, Hobo R, Leurs L J, Daenens K, Buth J, Myhre H O
University Hospital, Trondheim, Norway.
Eur J Vasc Endovasc Surg. 2005 Apr;29(4):363-70. doi: 10.1016/j.ejvs.2005.01.004.
To investigate the results following endovascular treatment of patients with inflammatory abdominal aortic aneurysms (IAAA).
Retrospective study based on the EUROSTAR registry.
Patients included in the EUROSTAR registry with IAAA (n=52, 1.4%) were compared to those having aneurysms without aortic fibrosis (n=3613, 98.6%). The mean follow-up period in patients with IAAA was 23 months (range 1-60). In 11 of the patients detailed information on the effect of endovascular repair and perianeurysmal fibrosis and ureteral entrapment was obtained by a dedicated questionnaire.
Twelve patients (23%) with IAAA had preoperative impairment of renal function and five had known hydronephrosis. Variables that were significantly associated with IAAA included younger age (p<.0001, mean difference 5.9, CI 3.7-7.9) and lower pulmonary risks score (OR 0.38, CI 0.19-0.74). At completion of the endovascular procedure, device stenosis was more frequently observed in patients with IAAA (OR 18.1, CI 3.52-93.0). There were no differences with regard to the rates of mortality, rupture or conversion in patients with IAAA and controls. In the majority, the aneurysm size regressed irrespective of nature of aneurysm. Of the 11 patients with a detailed assessment three had deterioration of renal function and three still had ureteral entrapment during follow-up.
Despite persistence of perianeurysmal inflammation in a proportion of patients operative and midterm results of endovascular repair were comparable in the patients with inflammatory and standard AAA.
研究炎症性腹主动脉瘤(IAAA)患者血管内治疗的效果。
基于欧洲血管内治疗登记系统(EUROSTAR)的回顾性研究。
将EUROSTAR登记系统中纳入的IAAA患者(n = 52,1.4%)与无主动脉纤维化的动脉瘤患者(n = 3613,98.6%)进行比较。IAAA患者的平均随访期为23个月(范围1 - 60个月)。通过专门问卷获取了11例患者血管内修复效果、瘤周纤维化及输尿管受压情况的详细信息。
12例(23%)IAAA患者术前存在肾功能损害,5例已知有肾积水。与IAAA显著相关的变量包括年龄较轻(p <.0001,平均差异5.9,可信区间3.7 - 7.9)和较低的肺部风险评分(比值比0.38,可信区间0.19 - 0.74)。血管内手术完成时,IAAA患者更常观察到器械狭窄(比值比18.1,可信区间3.52 - 93.0)。IAAA患者与对照组在死亡率、破裂率或中转开放手术率方面无差异。大多数情况下,无论动脉瘤性质如何,动脉瘤大小均缩小。在11例进行详细评估的患者中,3例在随访期间肾功能恶化,3例仍存在输尿管受压。
尽管部分患者瘤周炎症持续存在,但炎症性腹主动脉瘤患者与标准腹主动脉瘤患者血管内修复的手术及中期效果相当。