酿酒酵母第三条染色体上HMR区域的序列。

Sequence of the HMR region on chromosome III of Saccharomyces cerevisiae.

作者信息

Sor F, Chéret G, Fabre F, Faye G, Fukuhara H

机构信息

Institut Curie, Section de Biologie, Centre Universitaire, Orsay, France.

出版信息

Yeast. 1992 Mar;8(3):215-22. doi: 10.1002/yea.320080307.

DOI:10.1002/yea.320080307

PMID:1574927

Abstract

A 10,095 base pair DNA fragment from the right arm of chromosome III of Saccharomyces cerevisiae has been sequenced and analysed. It encompasses the silent mating-type locus HMR. Both HMRa1 and HMRa2 genes, as well as their flanking regulatory regions, have been identified. Three new open reading frames longer than 80 amino acid residues were found in this fragment. One of them (YCR137) shows features compatible with a membranous localization and a transporter function. The other two do not show a similarity with any known gene. A new gene coding for tRNA(thr)al (ACU) has been identified. It is located in a region coding for several delta sequences.

摘要

对来自酿酒酵母第三条染色体右臂的一段10,095个碱基对的DNA片段进行了测序和分析。它包含沉默交配型位点HMR。已鉴定出HMRa1和HMRa2基因及其侧翼调控区域。在该片段中发现了三个新的开放阅读框，其长度超过80个氨基酸残基。其中一个（YCR137）显示出与膜定位和转运功能相符的特征。另外两个与任何已知基因均无相似性。已鉴定出一个编码tRNA(thr)al（ACU）的新基因。它位于编码几个δ序列的区域。