与利奈唑胺治疗相关的视神经病变。
Optic neuropathy associated with linezolid treatment.
作者信息
McKinley Steven H, Foroozan Rod
机构信息
Cullen Eye Institute, Department of Ophthalmology, Baylor College of Medicine, Houston, TX 77030, USA.
出版信息
J Neuroophthalmol. 2005 Mar;25(1):18-21. doi: 10.1097/00041327-200503000-00005.
Abstract
Two patients undergoing long-term treatment with linezolid for pneumonia had decreased visual acuity, dyschromatopsia, and cecocentral scotomas characteristic of toxic optic neuropathy. Visual function slowly recovered 3 to 4 months after discontinuation of the antibiotic treatment in both patients. Toxic optic neuropathy may occur from linezolid. Early withdrawal of the antibiotic may be associated with visual recovery.
摘要
两名因肺炎接受长期利奈唑胺治疗的患者出现了视力下降、色觉异常以及中毒性视神经病变特有的中心暗点。两名患者在停用抗生素治疗后3至4个月，视觉功能缓慢恢复。利奈唑胺可能会引发中毒性视神经病变。早期停用抗生素可能与视力恢复有关。
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