利奈唑胺中毒性视神经病变：一例报告及视觉预后综述。
Linezolid toxic optic neuropathy: A case report and review of visual prognosis.
作者信息
Toolan Kevin J, Fondriest Jacob, Keenan Kaitlin, Mizen Thomas, Stosic Milena
机构信息
Department of Ophthalmology, Rush University, Chicago, IL, USA.
Department of Neurological Sciences Faculty and Staff, Rush University, Chicago, IL, USA.
出版信息
Am J Ophthalmol Case Rep. 2023 Aug 26;32:101922. doi: 10.1016/j.ajoc.2023.101922. eCollection 2023 Dec.
PURPOSE
To describe a case of linezolid toxic optic neuropathy in a 71-year-old female and review the relevant literature.
OBSERVATIONS
An adult female with progressive, symmetric vision loss was hypothesized to have linezolid toxic optic neuropathy. Following cessation of linezolid, the patient experienced improvement in visual function over two months.
CONCLUSIONS AND IMPORTANCE
Patients diagnosed with linezolid toxic optic neuropathy can expect some return of visual function after cessation. The degree of return does not correlate to the cumulative dose of the drug. The goal of this study was to summarize and add to the current body of literature on the topic.
目的
描述一例71岁女性的利奈唑胺中毒性视神经病变病例并回顾相关文献。
观察结果
一名成年女性出现进行性、对称性视力丧失，推测为利奈唑胺中毒性视神经病变。停用利奈唑胺后，患者在两个月内视觉功能有所改善。
结论与意义
被诊断为利奈唑胺中毒性视神经病变的患者在停药后视力功能有望部分恢复。恢复程度与药物累积剂量无关。本研究的目的是总结并补充该主题的现有文献。
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