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一例由胃食管反流(GER)引起的慢性持续性咳嗽(CPC)(包括对疑似GER引起的CPC的研究)

[A case of chronic persistent cough (CPC) caused by gastroesophageal reflux (GER) (including a study of CPC caused by suspected GER)].

作者信息

Fujimori K, Satoh M, Sasagawa M, Suzuki E, Arakawa M

机构信息

Department of Medicine (II), Niigata University School of Medicine.

出版信息

Arerugi. 1992 Mar;41(3):454-8.

PMID:1575643
Abstract

A patient, an 80-year-old female, had complained of a cough for 20 weeks, and was not cured by cough medicine. Gastroesophageal reflux was considered as the cause of the cough because of her symptoms and gastrointestinal fiberscopy (GIF) and barium meal studies. She made favorable progress on a histamine H2 blocker and cysapurid for 4 weeks. Therefore we diagnosed her cough as caused by gastroesophageal reflux. We also studied the incidence of chronic persistent cough in patients suspected of gastroesophageal reflux because of symptoms and GIF results. Among 676 cases examined by GIF at Niigata-kenritsu Myoko Hospital, we detected 7 cases who complained of heartburn and in whom we observed hiatal hernia and reflux esophagitis by GIF. Only one of them, the present case, complained of a cough. CPC caused by gastroesophageal reflux is not seen frequently, but the possibility of GER as the cause of CPC should be considered.

摘要

一名80岁女性患者,咳嗽20周,服用止咳药未治愈。因其症状以及胃肠纤维内镜检查(GIF)和钡餐检查结果,考虑胃食管反流为咳嗽病因。她服用组胺H2受体阻滞剂和西沙必利4周后病情好转。因此,我们诊断她的咳嗽是由胃食管反流引起的。我们还研究了因症状和GIF结果怀疑胃食管反流的患者中慢性持续性咳嗽的发生率。在新潟县立妙高医院接受GIF检查的676例患者中,我们发现7例主诉烧心,且通过GIF观察到食管裂孔疝和反流性食管炎。其中只有本例主诉咳嗽。由胃食管反流引起的慢性持续性咳嗽并不常见,但应考虑胃食管反流作为慢性持续性咳嗽病因的可能性。

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