Scheidegger E Paul, Itin Peter, Kempf Werner
Dept. of Dermatology, Kantonsspital Aarau, 501.1 Aarau, Switzerland.
Eur J Dermatol. 2005 Mar-Apr;15(2):70-2.
Primary cutaneous mucinosis encompasses a wide range of different skin conditions with circumscribed, follicular or diffuse manifestation. For the first time, to our knowledge, we report on the occurrence of so-called "atypical" localized papular mucinosis in the axillary pits of a mother and her (identical) twin daughters presenting as asymptomatic soft minuscule papules. This unique observation allows us to define an autosomal dominant inheritance pattern with a high level of penetrance for this rare skin disease.
原发性皮肤黏蛋白病涵盖了一系列不同的皮肤疾病,表现为局限性、毛囊性或弥漫性。据我们所知,我们首次报告了在一位母亲及其(同卵)双胞胎女儿的腋窝出现所谓“非典型”局限性丘疹性黏蛋白病,表现为无症状的柔软微小丘疹。这一独特观察结果使我们能够确定这种罕见皮肤病的常染色体显性遗传模式,其外显率很高。